medgadget | Opioids are the most widely prescribed medications to treat moderate
to severe chronic pain. These analgesics are used to manage pain in
cancer patients and also to treat severe constant pain in patients
suffering from terminal illnesses. These are generally administered via
subcutaneous, oral and intramuscular routes; other routes of
administration include nasal insufflations, patient controlled
analgesia, transdermal and oral mucosa routes via lozenges. Opioids can
be classified into three major classes namely, strong agonists
(fentanyl, oxymorphone, and morphine), mild to moderate agonists
(codeine and hydroxycodone), and opioids with mixed receptor reactions
(buprenophrine and pentazocine). Although they form one of the most
widely used analgesic classes, they cause certain adverse effects such
as constipation, nausea, vomiting, sedation, respiratory depression and
others. However, the major concern with this drug class is the high
level of drug abuse observed worldwide, leading to illegal trade of
these drugs worth hundreds of billions of dollars. According to a study
published in the Journal of American Medical Association in April 2011,
the rate of deaths occurring due to the overdose of prescription opioids
has increased substantially in the last decade in the U.S. alone. This
study also indicated that high doses of opioid drugs prescribed for pain
management possessed increased risk of overdose mortality in the
patients.
This report gives readers a comprehensive overview of the Opioids Market: http://www.transparencymarketresearch.com/opioids-market.html
The leading molecules in this segment that constituted about 65% of
the total opioids market include OxyContin (oxycodone), Nucynta
(tapentadol), Rybix and Ultram (tramadol), Exalgo (hydromorphone),
Ultiva (remifentanil) and fentanyl.The remaining 35% market revenue was
contributed by other generic opioids as well as combination formulations
of NSAIDs with opioids.The actual market scenario for this drug class,
however, could be different due to the strong product pipeline, with two
major entries MoxDuo IR (morphine/oxycodone) and Remoxy (oxycodone) set
to hit the market in 2016. The market entry of these two drugs is
expected to boost growth of the overall opioids market during the
forecast period. The number of patients suffering from chronic pain is
on a constant rise globally. Thus, increasing incidence of chronic pain
conditions will continue to encourage the use of pain management drugs,
thereby driving the opioids market. Doctors usually prescribe medicines
in the initial stages of pain, followed by other treatment options.
Prescription drugs are easy to use and economical and are expected to
support the growth of the opioids market globally.
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