yomiuri shimbun | During the Tokyo Olympics, Delta strains originating in India raged and the number of infected people continues to increase. Why is Japan not trying to use ivermectin, which has few reports of side effects and has been reported to be effective in clinical trials in other countries? On August 5, we had an urgent interview with Mr. Ozaki, chairman of the Tokyo Metropolitan Medical Association, who had been proposing effective uses of ivermectin from early on.
The peak of infection spread that is not yet visible
――It seems that the explosive spread of infection, which is also called the 5th wave, is still rising. The number of people waiting at home and receiving medical treatment is increasing rapidly. How is the Tokyo Metropolitan Medical Association responding?
"When the number of people waiting at home and receiving medical treatment increased sharply in the third wave of January, this was no good, and the Tokyo Metropolitan Medical Association and the Tokyo Metropolitan Medical Association worked together to build a system with the goal of 24-hour support. We have been able to handle up to 37 of the 47 district medical associations. However, the current situation where more than 1000 home caregivers are piled up every day is beyond the limit. , Vaccination, medical examination, home visit, etc. are not available. Now, the health center is coordinating hospitalization. There is also a hospitalization coordinating center in Tokyo, but there is a system that can quickly accept and treat suddenly changed corona patients. I haven't gotten to the point of being established. "
Many clinical trial results are "effective for prevention and treatment"
--If you read the papers on clinical trials of ivermectin that have been published around the world, there are many examples that are effective for both prevention and treatment.
"I am aware that there are many papers that ivermectin is effective in the prevention and treatment of corona, mainly in Central and South America and Asia. There is no effective therapeutic drug, although it is necessary to deal with patients who develop it one after another. The vaccine is not in time. At such an imminent time, there is a paper that ivermectin is effective for corona, so it is a natural response for clinicians to try using it. Doctor-led clinical practice That's why many test papers came out. "
--Usually, pharmaceutical companies conduct large-scale clinical trials to see the effects, but ivermectin has been selected by the World Health Organization (WHO) as a silver bullet for tropical diseases such as onchocerciasis (river blindness) and lymphatic filariasis. It is a drug approved by countries around the world more than 20 years ago. If it is effective for the new corona, it is not applicable, but it is unavoidable that we decided to use it in a pandemic.
"That's right. The medical field of a pandemic is a battlefield. It's the same as a field hospital. Patients are brought in and their condition deteriorates one after another and they die. So I can understand the feelings of the doctor who clings to this and administers it. "
"The other day, a research group at the All India Institute of Medical Sciences / AIIMS, which sets guidelines for the treatment of corona infections in India, has published a paper investigating the preventive effects of ivermectin. According to the report, about 3,900 medical workers (staff and students) were given 0.3 mg / kg of ivermectin twice at 3-day intervals, only once, and then. As a result of conducting clinical trials divided into three groups of those who did not, it is said that those who received ivermectin twice reduced the new corona infection by 83%. It was the first time in the world to publish a paper. It's a class research group, so it's very reliable. "
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