the dopamine hypothesis...,

frontiersin |  Dopamine is an inhibitory neurotransmitter involved in the pathology of schizophrenia. The revised dopamine hypothesis states that dopamine abnormalities in the mesolimbic and prefrontal brain regions exist in schizophrenia. However, recent research has indicated that glutamate, GABA, acetylcholine, and serotonin alterations are also involved in the pathology of schizophrenia. This review provides an in-depth analysis of dopamine in animal models of schizophrenia and also focuses on dopamine and cognition. Furthermore, this review provides not only an overview of dopamine receptors and the antipsychotic effects of treatments targeting them but also an outline of dopamine and its interaction with other neurochemical models of schizophrenia. The roles of dopamine in the evolution of the human brain and human mental abilities, which are affected in schizophrenia patients, are also discussed.

the ukraine crisis as told through hip-hop

foreignpolicy |  Weapons cocked, a group of well-armed young men rap about their hatred for the government. It sounds like a scene straight from a ‘90s gangsta rap video, but it isn't -- it's from the frontlines of Ukraine's violent east. 

Inspired by the recent turmoil, Ukraine's young, burgeoning hip-hop community has taken to interpreting its country's politics through its music, providing an unlikely and unfiltered window into the unfolding scene there. Their music videos, posted on YouTube, tell the story: Anger toward former President Viktor Yanukovych, distrust of the interim government, anxiety over the annexation of Crimea, and taunts for government forces in the east. 

Here, then, is the hip-hop guide to the Ukrainian crisis: 

Many have forgotten that the crisis began as a peaceful protest against Yanukovych. Under his rule, corruption in Ukraine spiraled out of control, with Ukraine ranking 144 out of 177 on Transparency International's 2013 Corruption Perceptions Index. Resentment toward Yanukovych's presidency and a desire among many Ukrainians to forge ahead finally crystallized in the Maidan protest movement. 

Cue the following video. Made in December 2013, the song features Ukrainian YouTube personality Michael Shchur rapping about the corruption of Yanukovych's regime while walking through the Maidan at night. Referring to Yanukovych and his decadent lifestyle paid for out of the state coffers, Shchur sums up the sense of palatable disgust: "Your childhood dream became a reality/You have shoes made of ostrich leather, a couple Italian suits/You got them from nowhere, almost for free."

the rise of the nipster

rollingstone | Coincidentally or not, the emergence of the nipster has taken place at the same time as the rise of a new far-right political scene in Europe: In this May's European elections, the National Front — the anti-immigrant party headed by Marine Le Pen — won the biggest voting share of parties in the French elections, and the British United Kingdom Independence Party won 27.5 percent of the vote in the U.K. Many people link these parties' success to their ability to package themselves as a friendlier, less-threatening far right. Dutch political scientist Cas Mudde has argued that these parties largely swept into power by linking the euro crisis "to their core ideological features: nativism, authoritarianism and populism." 

The current German wave of, for instance, hip, vegan neo-Nazis functions in a similar way. Rafael says they attempt to slide into debates where young people wouldn't expect them, and then sell their politics as a palatable outlet. "They use subjects like globalization and animal protection as entry points, and then offer a very simple worldview that makes complex subjects very easy to understand," says Rafael. "Of course, in the end, it's always about racism and anti-Semitism and nationalism."  The danger — in both cases — is that extreme-right positions might quietly shift into the mainstream.

Over the past two years, Cynthia Miller-Idriss, an associate professor at American University in Washington, D.C., has been conducting research with young people in Berlin schools who are on the periphery of the extreme-right. She says that, if anything, the change in neo-Nazi fashion has made it more difficult to step in when young people are being embroiled in the scene. "If you were a teacher," she says, "you used to be able to identify a skinhead in your class and you could think of ways to intervene. But now it's harder to mainstream society to understand who these young people are and to engage with them."

Miller-Idriss suggests that for a generation raised on Facebook and Twitter, it may no longer feel ridiculous to, say, love Rihanna in real life but disparage black people on Facebook. "The social media space allows young people to have different expressions of their identities in different places," she says. "This generation of youth likes the idea of having more control over their own identity. They've realized your style doesn't have to be connected to your ideology. You can dress however you want to and still be a neo-Nazi."

With this in mind, Koehler thinks there is a need in Germany for a new, broader educational campaign on how to identify members of the extreme right. "A short while ago we did a study with judges and lawyers, who thought they weren't encountering neo-Nazis because they weren't seeing any skinheads," he says, "but they have no idea anymore what a neo-Nazi looks like."

chimps prefer african and indian music

science20 |  When African and Indian music was played near their large outdoor enclosures, the chimps spent significantly more time in areas where they could best hear the music. When Japanese music was played, they were more likely to be found in spots where it was more difficult or impossible to hear the music. The African and Indian music in the experiment had extreme ratios of strong to weak beats, whereas the Japanese music had regular strong beats, which is also typical of Western music.

"Chimpanzees may perceive the strong, predictable rhythmic patterns as threatening, as chimpanzee dominance displays commonly incorporate repeated rhythmic sounds such as stomping, clapping and banging objects," said de Waal.

Sixteen adult chimps in two groups participated in the experiment at the Yerkes National Primate Research Center at Emory University. Over 12 consecutive days for 40 minutes each morning, the groups were given the opportunity to listen to African, Indian or Japanese music playing on a portable stereo near their outdoor enclosure. Another portable stereo not playing any music was located at a different spot near the enclosure to rule out behavior that might be associated with an object rather than the music.

The different types of music were at the same volume but played in random order. Each day, researchers observed the chimps and recorded their location every two minutes with handwritten notes. They also videotaped the activity in the enclosure. The chimps' behavior when the music was played was compared to their behavior with no music.

"Chimpanzees displaying a preference for music over silence is compelling evidence that our shared evolutionary histories may include favoring sounds outside of both humans' and chimpanzees' immediate survival cues," said lead author Morgan Mingle, BA, of Emory and Southwestern University in Austin. "Our study highlights the importance of sampling across the gamut of human music to potentially identify features that could have a shared evolutionary root."

musical and spatial representation

frontiersin |  Consistent evidence suggests that pitch height may be represented in a spatial format, having both a vertical and a horizontal representation. The spatial representation of pitch height results into response compatibility effects for which high pitch tones are preferentially associated to up-right responses, and low pitch tones are preferentially associated to down-left responses (i.e., the Spatial-Musical Association of Response Codes (SMARC) effect), with the strength of these associations depending on individuals’ musical skills. In this study we investigated whether listening to tones of different pitch affects the representation of external space, as assessed in a visual and haptic line bisection paradigm, in musicians and non musicians. Low and high pitch tones affected the bisection performance in musicians differently, both when pitch was relevant and irrelevant for the task, and in both the visual and the haptic modality. No effect of pitch height was observed on the bisection performance of non musicians. Moreover, our data also show that musicians present a (supramodal) rightward bisection bias in both the visual and the haptic modality, extending previous findings limited to the visual modality, and consistent with the idea that intense practice with musical notation and bimanual instrument training affects hemispheric lateralization.

about that practice making perfect....,

sciencedaily |  Mom or dad may have driven you to cello rehearsal all those years, but you can also thank your genes for pushing you to practice, according to new research led by a Michigan State University professor. 

Genetics and environment work together to help people become accomplished musicians, finds the study of 850 sets of twins. It's another arrow in the quiver of the argument that both nature and nurture play a role in developing expertise.

"The nature vs. nurture debate has raged since the beginning of psychology," said Zach Hambrick, MSU professor of psychology. "This makes it very clear that it's both. Not only in the sense that both nature and nurture contribute, but that they interact with each other."

The study breaks new ground in ascertaining the specific roles of genes. Essentially, it found:

• Accomplished musicians practiced much more than those who weren't accomplished.
• That propensity to practice was fueled partly by genetics, which the researchers were able to establish by comparing identical twins, who share 100 percent of their genes, with fraternal twins, who share 50 percent of their genes. The finding suggests genetics influence the sorts of activities we pursue.
• When it came to music accomplishment, genes had a bigger influence on those who practiced than those who didn't.

Writers such as Malcolm Gladwell argue that experts are almost entirely "made" and that a lack of innate ability can be overcome with enough training. The way to master that cello, in other words, is to practice for at least 10,000 hours, as past research has suggested.

But the new study challenges that theory by showing genes had a major contribution on the musicians who practiced and became successful. For those who didn't practice, there was essentially no genetic contribution.

"Contrary to the view that genetic effects go away as you practice more and more," Hambrick said, "we found that genes become more important in accounting for differences across people in music performance as they practice."

mandatory sentencing for medical marijuana...,

NYTimes |  How did the United States, land of the free, become the world’s top jailer? It’s a question asked by visitors from other democracies, and the American citizen who wakes from a stupor to find that our prisons are stuffed with people serving interminable sentences for nonviolent crimes.

For the answer, you need look no further than the real America, the sparsely settled, ruggedly beautiful, financially struggling eastern third of Washington State. There, 70-year-old Larry Harvey, his wife, two family members and a friend are facing mandatory 10-year prison terms for growing medical marijuana — openly and, they thought, legally — on their farm near the little town of Kettle Falls.

To get a sense of the tragic absurdity of this federal prosecution, reaching all the way to the desk of Attorney General Eric H. Holder Jr., consider what will happen next month. Pot stores will open in Washington, selling legal marijuana for the recreational user — per a vote of the people. A few weeks later, the Feds will try to put away the so-called Kettle Falls Five for growing weed on their land to ease their medical maladies. Federal sentencing guidelines, which trump state law, call for mandatory prison terms.

Harvey is a former long-haul truck driver with a bad knee, spasms of gout and high blood pressure. He says he has no criminal record, and spends much of his time in a wheelchair. His wife, Rhonda Firestack-Harvey, is a retired hairdresser with arthritis and osteoporosis. Mr. Harvey says he takes his wife’s home-baked marijuana confections when the pain in his knee starts to flare. The Harveys thought they were in the clear, growing 68 marijuana plants on their acreage in northeast Washington, one of 22 states allowing legal medical marijuana. (Federal authorities say they are several plants over the limit.)

Their pot garden was a co-op among the four family members and one friend; the marijuana was not for sale or distribution, Mr. Harvey says. “I think these patients were legitimate,” Dr. Greg Carter, who reviewed medical records after the arrest, told The Spokesman-Review of Spokane. “They are pretty normal people. We’re not talking about thugs.”

But the authorities, using all the military tools at their disposal in the exhausted drug war, treated them as big-time narco threats. First, a helicopter spotted the garden from the air. Brilliant, except Harvey himself had painted a huge medical marijuana sign on a plywood board so that his garden, in fact, could be identified as a medical pot plot from the air.

This was followed by two raids. One from eight agents in Kevlar vests. The other from Drug Enforcement Agency officers. They searched the house, confiscating guns, and a little cash in a drawer. The guns are no surprise: Finding someone who does not own a firearm in the Selkirk Mountain country is like finding a Seattleite who doesn’t recycle. Still, the guns were enough to add additional federal charges to an indictment that the family was growing more than the legal limit of plants.

the catch-22 of medical marijuana science

NYTimes |  New York moved last week to join 22 states in legalizing medical marijuana for patients with a diverse array of debilitating ailments, encompassing epilepsy and cancer, Crohn’s disease and Parkinson’s. Yet there is no rigorous scientific evidence that marijuana effectively treats the symptoms of many of the illnesses for which states have authorized its use.

Instead, experts say, lawmakers and the authors of public referendums have acted largely on the basis of animal studies and heart-wrenching anecdotes. The results have sometimes confounded doctors and researchers.

The lists of conditions qualifying patients for marijuana treatment vary considerably from state to state. Like most others, New York’s includes cancer, H.I.V./AIDS and multiple sclerosis. Studies have shown that marijuana can relieve nausea, improve appetite and ease painful spasms in those patients.

But New York’s list also includes Parkinson’s disease, Lou Gehrig’s disease and epilepsy, conditions for which there are no high-quality trials indicating marijuana is useful. In Illinois, more than three dozen conditions qualify for treatment with marijuana, including Alzheimer’s disease, lupus, Sjogren’s syndrome, Tourette’s syndrome, Arnold-Chiari malformation and nail-patella syndrome.

“I just don’t think the evidence is there for these long lists,” said Dr. Molly Cooke, a professor of medicine at the University of California, San Francisco, who helped research a position paper on cannabis for the American College of Physicians. “It’s been so hard to study marijuana. Policy makers are responding to thin data.”

Even some advocates of medical marijuana acknowledge that the state laws legalizing it did not result from careful reviews of the medical literature.

“I wish it were that rational,” said Mitch Earleywine, chairman of the executive board of directors for Norml, a national marijuana advocacy group. Dr. Earleywine said state lawmakers more often ask themselves, “What disease does the person in a wheelchair in my office have?”

Research into marijuana’s effects is thin not because of a lack of scientific interest, but chiefly because the federal government has long classified it as a Schedule 1 drug with “no currently accepted medical use.” Scientists who want to conduct studies must register with the Drug Enforcement Administration and win the approval of the National Institute on Drug Abuse, which is the only supplier of legal, research-grade marijuana and can decline to supply it.

purportedly progressive massachusetts has a "private" SWAT network...,

WaPo | As part of the American Civil Liberties Union’s recent report on police militarization, the Massachusetts chapter of the organization sent open records requests to SWAT teams across that state. It received an interesting response.

As it turns out, a number of SWAT teams in the Bay State are operated by what are called law enforcement councils, or LECs. These LECs are funded by several police agencies in a given geographic area and overseen by an executive board, which is usually made up of police chiefs from member police departments. In 2012, for example, the Tewksbury Police Department paid about $4,600 in annual membership dues to the North Eastern Massachusetts Law Enforcement Council, or NEMLEC. (See page 36 of linked PDF.) That LEC has about 50 member agencies. In addition to operating a regional SWAT team, the LECs also facilitate technology and information sharing and oversee other specialized units, such as crime scene investigators and computer crime specialists.

Some of these LECs have also apparently incorporated as 501(c)(3) organizations. And it’s here that we run into problems. According to the ACLU, the LECs are claiming that the 501(c)(3) status means that they’re private corporations, not government agencies. And therefore, they say they’re immune from open records requests. Let’s be clear. These agencies oversee police activities. They employ cops who carry guns, wear badges, collect paychecks provided by taxpayers and have the power to detain, arrest, injure and kill. They operate SWAT teams, which conduct raids on private residences. And yet they say that because they’ve incorporated, they’re immune to Massachusetts open records laws. The state’s residents aren’t permitted to know how often the SWAT teams are used, what they’re used for, what sort of training they get or who they’re primarily used against.

(Read more: New ACLU report confirms the stunning rise in police militarization)

self-powered flow-induction on the event horizon...,

neurologica |  Energy is what makes stuff happen. The ability to generate energy in useful amounts and locations is key to our civilization. Often when discussing energy we are focusing on big energy, how to make large amounts of energy in a cost-effective manner with minimal negative impact on our environment.

The ability to generate tiny amounts of energy is also useful, however. One particular application requiring a small but reliable source of energy is implantable devices, such as cardiac pacemakers. Right now pacemakers are run by small batteries. These batteries have a limited lifespan, and need to be surgically replaced.

What if, however, we could generate the required electrical energy from the body itself. Our bodies use a relative large amount of energy, creating movement, electrical signals, generating heat, assembling proteins and cells, and undergoing biochemical reactions. All we would need to do is tap into a tiny slice of this energy and there would be enough energy to power a pacemaker, or many other small implantable devices.

A recent paper discusses a successful demonstration of one such technology. Hwang et. al. report:

A flexible single crystalline PMN-PT piezoelectric energy harvester is demonstrated to achieve a self-powered artificial cardiac pacemaker. The energy harvesting device generates a short-circuit current of 0.223 mA and an open-circuit voltage of 8.2 V, which are enough to meet the standard for not only charging commercial batteries but also stimulating heart without an external power source.

The piezoelectric effect is a property of some materials that converts mechanical stress into electrical current. In the body, mechanical stress can derive from the beating of the heart, the movement of the chest wall in breathing, the movement of limbs, or the bouncing movement of walking. The idea of harvesting electricity from such movement through the piezoelectric effect has been around for a while, and it’s good to see a successful demonstration of this principle.

Other types of devices that could benefit from this technology include hearing aids, medication pumps, vagal nerve or deep-brain stimulators, and implantable sensors (such as blood glucose monitors).

The technology could also be used for wearable or portable electronic devices. Flexible piezoelectric devices could provide extra juice to your cell phone, extending the life of its charge, or even providing an emergency charge if you are away from an outlet.

It’s likely that the technology would also give a boost to the development of new wearable electronics applications. A major limitation of such technology is providing convenient power.

the importance of feelings

TechnologyReview | For decades, biologists spurned emotion and feeling as uninteresting. But Antonio Damasio demonstrated that they were central to the life-regulating processes of almost all living creatures.

Damasio’s essential insight is that feelings are “mental experiences of body states,” which arise as the brain interprets emotions, themselves physical states arising from the body’s responses to external stimuli. (The order of such events is: I am threatened, experience fear, and feel horror.) He has suggested that consciousness, whether the primitive “core consciousness” of animals or the “extended” self-conception of humans, requiring autobiographical memory, emerges from emotions and feelings.

His insight, dating back to the early 1990s, stemmed from the clinical study of brain lesions in patients unable to make good decisions because their emotions were impaired, but whose reason was otherwise unaffected—research made possible by the neuroanatomical studies of his wife and frequent coauthor, Hanna Damasio. Their work has always depended on advances in technology. More recently, tools such as functional neuroimaging, which measures the relationship between mental processes and activity in parts of the brain, have complemented the Damasios’ use of neuroanatomy.

A professor of neuroscience at the University of Southern California, Damasio has written four artful books that explain his research to a broader audience and relate its discoveries to the abiding concerns of philosophy. He believes that neurobiological research has a distinctly philosophical purpose: “The scientist’s voice need not be the mere record of life as it is,” he wrote in a book on ­Descartes. “If only we want it, deeper knowledge of brain and mind will help achieve … happiness.”

Antonio Damasio talked with Jason Pontin, the editor in chief of MIT Technology Review.

a nugget obscured by a muddled puddle of shyte...,

Forbes |  In her now classic book, Animals in Translation, Colorado State University professor of animal science Temple Grandin argues that most mammals seem incapable of feeling fear and curiosity at the same time—meaning the presence of one inhibits the other.

Something similar also shows up in the research around flow. It appears that flow (that is, optimal performance) is the exact opposite of fight-or-flight—something I explain in Rise of Superman:

The fight-or-flight response—a.k.a. the adrenaline rush—cocktails adrenaline, cortisol (the stress hormone), and norepinephrine. It’s an extreme stress response. The brain switches to reactive survival autopilot. Options are limited to three: fight, flee, or freeze. Flow is the opposite: a creative problem-solving state, options wide open.

Yet there are reasons for the confusion. The two highs are linked. Risk heightens focus and flow follows focus. This means that the fight-or-flight response primes the body—chemically and psychologically—for the flow state. Athletes report moving through one to get to the other. [Skateboard legend] Danny Way, for example, has a phrase he uses to remind himself of the importance of this transition. “Never a glitch on takeoff,” he says. He means that when you’re teetering between flow and fight-or-flight, all it takes is one errant thought to send you in the wrong direction. When Way pushes off onto the megaramp, he has seconds to flip this switch. If he can follow his focus into flow he lives to ride another day. But if panic swamps the circuitry? “The greatest slams of my life took place when that happened,” he says. “Almost every time, I’ve ended up in the hospital.”

Of course, it’s early days for these sorts of ideas, but what the science is suggesting is evolution has overlaid instinctive, anti-social fear-based traits—things that narrow our options and responses—with more pro-social traits that widen options and responses. This may mean that  we can make radical improvements in ourselves, our organizations and our society by training up skills like flow, curiosity and empathy as a way of training down violence, prejudice, and fear.

In other words, peace on earth is now moving out of the field of dreams and into the laboratory and, honestly, not a moment to lose.

*For more access to similar ideas, sign up for Flow Hacker Nation, the email newsletter for the Flow Genome Project.

hegemony recklessly eyeballing weed, genes, the spectrum....,

kingscollegelondon | The researchers found that people genetically pre-disposed to schizophrenia were more likely to use cannabis, and use it in greater quantities than those who did not possess schizophrenia risk genes. 

Power says: “We know that cannabis increases the risk of schizophrenia. Our study certainly does not rule this out, but it suggests that there is likely to be an association in the other direction as well – that a pre-disposition to schizophrenia also increases your likelihood of cannabis use.” 

“Our study highlights the complex interactions between genes and environments when we talk about cannabis as a risk factor for schizophrenia. Certain environmental risks, such as cannabis use, may be more likely given an individual’s innate behaviour and personality, itself influenced by their genetic make-up.  This is an important finding to consider when calculating the economic and health impact of cannabis.” 

Additional funding was provided by the National Institutes of Health, Australian National health and Medical Research Council, Australian Research Council, GenomEUtwin Project, Centre for Research Excellence on Suicide Prevention in Australia, the National Institute for Health Research Biomedical Research Centre (NIHR BRC) at the South London and Maudsley NHS Foundation Trust and King’s College London and the Netherlands Organization for Health Research and Development.  

Paper reference: Power, R. et al. ‘Genetic predisposition to schizophrenia associated with increased use of cannabis’ published in Molecular Psychiatry. 

uptight chickenshits playing soldier the most dangerous drug of all...,

Just look at that face - any more puckered and he'd burst a vein!

WaPo |  The American Civil Liberties Union has released the results of its year-long study of police militarization. The study looked at 800 deployments of SWAT teams among 20 local, state and federal police agencies in 2011-2012. Among the notable findings:

• 62 percent of the SWAT raids surveyed were to conduct searches for drugs.
• Just under 80 percent were to serve a search warrant, meaning eight in 10 SWAT raids were not initiated to apprehend a school shooter, hostage taker, or escaped felon (the common justification for these tactics), but to investigate someone still only suspected of committing a crime.
• In fact, just 7 percent of SWAT raids were “for hostage, barricade, or active shooter scenarios.”
• In at least 36 percent of the SWAT raids studies, no contraband of any kind was found. The report notes that due to incomplete police reports on these raids this figure could be as high as 65 percent.
• SWAT tactics are disproportionately used on people of color.
• 65 percent of SWAT deployments resulted in some sort of forced entry into a private home, by way of a battering ram, boot, or some sort of explosive device. In over half those raids, the police failed to find any sort of weapon, the presence of which was cited as the reason for the violent tactics.
• Ironically (or perhaps not), searches to serve warrants on people suspected of drug crimes were more likely to result in forced entry than raids conducted for other purposes.
• Though often justified for rare incidents like school shootings or terrorist situations, the armored personnel vehicles police departments are getting from the Pentagon and through grants from the Department of Homeland Security are commonly used on drug raids.

In other words, where violent, volatile SWAT tactics were once used only in limited situations where someone was in the process of or about to commit a violent crime — where the police were using violence only to defuse an already violent situation — SWAT teams today are overwhelmingly used to investigate people who are still only suspected of committing nonviolent consensual crimes. And because these raids often involve forced entry into homes, often at night, they’re actually creating violence and confrontation where there was none before.

When SWAT teams are used in a way that’s consistent with their original purpose, they’re used carefully and cautiously. The ACLU report finds that, “In nearly every deployment involving a barricade, hostage, or active shooter, the SWAT report provided specific facts that gave the SWAT team reason to believe there was an armed and often dangerous suspect.” By contrast . . .

 . . . incident reports for search warrant executions, especially in drug investigations, often contained no information about why the SWAT team was being sent in, other than to note that the warrant was “high risk,” or else provided otherwise unsubstantiated information such as “suspect is believed to be armed.” In case after case that the ACLU examined, when a SWAT team was deployed to search a person’s home for drugs, officers determined that a person was “likely to be armed” on the basis of suspected but unfounded gang affiliations, past weapons convictions, or some other factor that did not truly indicate a basis for believing that the person in question was likely to be armed at the moment of the SWAT deployment. Of course, a reasonable belief that weapons are present should not by itself justify a SWAT deployment. Given that almost half of American households have guns, use of a SWAT team could almost always be justified if this were the sole factor.

But we’ve already seen cases in which the mere factor that the resident of a home was a legal gun owner — in some cases by virtue of the fact that the owner had obtained some sort of state license — was used as an excuse to execute a full-on SWAT raid to serve a warrant for an otherwise nonviolent crime.

the secret plan to close social security's offices and outsource its work

commondreams |  For months there have been rumors that the Social Security Administration has a “secret plan” to close all of its field offices. Is it true? A little-known report commissioned by the SSA the request of Congress seems to hold the answer. The summary document outlining the plan, which is labeled “for internal use only,” is unavailable from the SSA but can be found here.

Does the document, entitled “Long Term Strategic Vision and Vision Elements,” really propose shuttering all field offices? The answer, buried beneath a barrage of obfuscatory consultantese, clearly seems to be “yes.” Worse, the report also suggests that many of the SSA’s critical functions could soon be outsourced to private-sector partners and contractors.

Here are five insights from this austerity-minded outline.

the mysterious history of marijuana (raises more kwestins than it answers)

npr | Marijuana has been intertwined with race and ethnicity in America since well before the word "marijuana" was coined. The drug, , has a disturbing case of multiple personality disorder: It's a go-to pop culture punch line. It's the foundation of a growing recreational and medicinal industry. , it's also the reason for more than half of the drug arrests in the U.S. A deeply disproportionate number of marijuana arrests (the vast majority of which are for possession) befall African-Americans, despite similar rates of usage among whites and blacks, the ACLU says.

Throughout the 19th century, news reports and medical journal articles almost always use the plant's formal name, cannabis. Numerous accounts say that "marijuana" came into popular usage in the U.S. in the early 20th century because anti-cannabis factions wanted to underscore the drug's "Mexican-ness." It was meant to play off of anti-immigrant sentiments.

A common version of the story of the criminalization of pot goes like this: Cannabis was outlawed because various powerful interests (some of which have economic motives to suppress hemp production) were able to craft it into a bogeyman in the popular imagination, by spreading tales of homicidal mania touched off by consumption of the dreaded Mexican "locoweed." Fear of brown people combined with fear of nightmare drugs used by brown people to produce a wave of public action against the "marijuana menace." That combo led to restrictions in state after state, ultimately resulting in federal prohibition.

But this version of the story starts to prompt more questions than answers when you take a close look at the history of the drug in the U.S.: What role did race actually play in the perception of the drug? Are historical accounts of pot usage — including references to Mexican "locoweed" — even talking about the same drug we know as marijuana today? How did the plant and its offshoots get so many darn names (reefer, pot, weed, hashish, dope, ganja, bud, and on and on and on) anyway? And while we're on the subject, how did it come to be called "marijuana"?

Let's start with the race question. Eric Schlosser recounts some of the racially charged history of marijuana in (some of the source material for the best-selling book):

"The political upheaval in Mexico that culminated in the Revolution of 1910 led to a wave of Mexican immigration to states throughout the American Southwest. The prejudices and fears that greeted these peasant immigrants also extended to their traditional means of intoxication: smoking marijuana. Police officers in Texas claimed that marijuana incited violent crimes, aroused a "lust for blood," and gave its users "superhuman strength." Rumors spread that Mexicans were distributing this "killer weed" to unsuspecting American schoolchildren. Sailors and West Indian immigrants brought the practice of smoking marijuana to port cities along the Gulf of Mexico. In New Orleans newspaper articles associated the drug with African-Americans, jazz musicians, prostitutes, and underworld whites. "The Marijuana Menace," as sketched by anti-drug campaigners, was personified by inferior races and social deviants."

In 1937, U.S. Narcotics Commissioner Henry Anslinger testified before Congress in the hearings that would result in the introduction of federal restrictions on marijuana. , Anslinger's testimony included a letter from Floyd Baskette, the city editor of the Alamosa (Colo.) Daily Courier, which said in part, "I wish I could show you what a small marihuana cigaret can do to one of our degenerate Spanish-speaking residents. That's why our problem is so great; the greatest percentage of our population is composed of Spanish-speaking persons, most of who [sic! such an enthusiastic sic!] are low mentally, because of social and racial conditions."

Folks weren't just worrying about Mexicans and jazz musicians, either. "Within the last year we in California have been getting a large influx of Hindoos and they have in turn started quite a demand for cannabis indica," wrote Henry J. Finger, a powerful member of California's State Board of Pharmacy, (page 18). "They are a very undesirable lot and the habit is growing in California very fast; the fear is now that it is not being confined to the Hindoos alone but that they are initiating our whites into this habit."

the emperor wears no clothes

READ THE BOOK ONLINE

the elkhorn manifesto: what do hemp and hitler have in common?

archive | Before the Gatewood Galbraith for Governor Campaign in 1991, few Kentuckians knew that the plant that the federal government had demonized for over 50 years as "Marijuana - Assassin of Youth," was, in fact, Cannabis Hemp, the most traded commodity in the world until the mid-1800s, and our state's number one crop, industry, and most important source of revenue, for over 150 years. 

Today, thanks to the efforts of pioneer hemp researchers and public advocates such as Galbraith, Jack Fraizer, Jack Herer, Chris Conrad, Ed Rosenthal, Don Wirtshafter and others, the federal government's unjustifiable suppression of our state's right to develop our most valuable and versatile natural resource, is facing increasing opposition from an informed public. Hemp is now recognized as the number one agriculturally renewable raw material in the world, and perhaps the only crop / industry which can guarantee us industrial and economic independence from the trans-national corporations.

"Shadow of the Swastika" is a follow-up to my earlier work, "Cannabis Hemp: the Invisible Prohibition Revealed," which I wrote and published in support of the Galbraith Campaign. Since publication of that booklet, there has been growing public acceptance of the evidence that Marijuana Prohibition was created in 1937, not to protect society from the "evils of the drug Marijuana," as the Federal government claimed, but as an act of deliberate economic and industrial sabotage against the re-emerging Industrial Hemp Industry.

Previous investigations by hemp researchers have been limited to the suppression of free-market competition from the hemp industry, and focused on the activities of three prominent members of America's corporate, industrial and banking establishment during the mid- to late-1930s:

WILLIAM RANDOLPH HEARST, the newspaper and magazine tycoon.

The expected rebirth of cannabis hemp as a less expensive source of pulp for paper meant his millions of acres of prime timberland, and investment in wood pulp papermaking equipment, would soon be worth much less. In the 1920s, about the same time as the equipment was developed to economically mass-produce raw hemp into pulp and fiber for paper, he began the "Reefer Madness" hoax in his newspaper and magazine publications.

ANDREW MELLON, founder of the Gulf Oil Corporation.

He knew that cannabis hemp was an alternative industrial raw material for the production of thousands of products, including fuel and plastics, which, if allowed to compete in the free-market, would threaten the future profits of the oil companies. As Secretary of the Treasury he created the Federal Bureau of Narcotics, and appointed his own future nephew-in-law, Harry Anslinger, as director. Anslinger would later use the sensational, and totally fabricated, articles published by Hearst, to push the Marijuana Tax Act of 1937 through Congress, which successfully destroyed the rebirth of the cannabis hemp industry. A prominent member of one Congressional subcommittee who voted in favor of this bill was Joseph Guffey of Pennsylvania, an oil tycoon and former business partner of Andrew Mellon in the Spindletop oil fields in Texas.

THE DU PONT CHEMICAL CORPORATION,

which owned the patents on synthetic petrochemicals and industrial processes that promised billions of dollars in future profits from the sale of wood pulp paper, lead additives for gasoline, synthetic fibers and plastics, if hemp could be suppressed. At the time, du Pont family influence in both government and the private sector was unmatched, according to historians and journalists.

This publication, however, reveals documented historical evidence that the suppression of the hemp industry was only one key part of a much larger conspiracy in the 1930s, not only by the three corporate interests named above, but by many others, as well. 

Congressional records, FBI reports and investigations by the Justice Department, during the 1930s and 1940s, have already documented evidence of this wider plot. A list of the corporations named include Du Pont, Standard Oil, and General Motors, all of which were proven to be conspiring with Nazi industrial cartels to eliminate competition world-wide and divide among themselves the Earth's industrial resources and commercial markets, for profitable exploitation.

This conspiracy succeeded. It is now obvious that this lack of serious competition in the industrial raw materials market caused our present - and totally contrived - addiction to petrochemicals. Its success is directly responsible for the most troubling problems we now face in the 1990s; serious damage to our environment, concentration of economic and political power into fewer and fewer hands, and the weakening of the rights of individuals and states to determine their own futures.

It is more and more evident that, given the historical record, the structure of the New World Order is being built upon the Foundation of Marijuana Prohibition, and only the relegalization of free-market hemp competition can save us.

R. William Davis
July 4, 1996
Louisville, Kentucky

the fascinating endocannabinoidal system

stanford |  A new study led by investigators at the Stanford University School of Medicine has implicated the blocking of endocannabinoids — signaling substances that are the brain’s internal versions of the psychoactive chemicals in marijuana and hashish — in the early pathology of Alzheimer’s disease.

A substance called A-beta — strongly suspected to play a key role in Alzheimer’s because it’s the chief constituent of the hallmark clumps dotting the brains of people with Alzheimer’s — may, in the disease’s earliest stages, impair learning and memory by blocking the natural, beneficial action of endocannabinoids in the brain, the study demonstrates. The Stanford group is now trying to figure out the molecular details of how and where this interference occurs. Pinning down those details could pave the path to new drugs to stave off the defects in learning ability and memory that characterize Alzheimer’s.

In the study, published June 18 in Neuron, researchers analyzed A-beta’s effects on a brain structure known as the hippocampus. In all mammals, this midbrain structure serves as a combination GPS system and memory-filing assistant, along with other duties.

“The hippocampus tells us where we are in space at any given time,” said Daniel Madison, PhD, associate professor of molecular and cellular physiology and the study’s senior author. “It also processes new experiences so that our memories of them can be stored in other parts of the brain. It’s the filing secretary, not the filing cabinet.” Fist tap Dale.

mysteries of morality

pdescioli |  Evolutionary theories of morality, beginning with Darwin, have focused on explanations for altruism. More generally, these accounts have concentrated on conscience (self-regulatory mechanisms) to the neglect of condemnation (mechanisms for punishing others). As a result, few theoretical tools are available for understanding the rapidly accumulating data surrounding third-party judgment and punishment. Here we consider the strategic interactions among actors, victims, and third-parties to help illuminate condemnation. Weargue that basic differences between the adaptive problems faced by actors and third-parties indicate that actor conscience and third-party condemnation are likely performed by different cognitive mechanisms. Further, we argue that current theories of conscience do not easily explain its experimentally demonstrated insensitivity to consequences. However, these results might be explicable if conscience functions, in part, as a defense system for avoiding third-party punishment. If conscience serves defensive functions, then its computational structure should be closely tailored to the details of condemnation mechanisms. This possibility underscores the need for a better understanding of condemnation, which is important not only in itself but also for explaining the nature of conscience. We outline three evolutionary mysteries of condemnation that require further attention: third-party judgment, moralistic punishment, and moral impartiality