Wednesday, November 03, 2010

gut bugs affect mating

The Scientist | Differences in diet alter the composition of microbiota in Drosophila, which appears to in turn influence mate preferences -- and drive speciation. Drosophila seem to prefer to mate with other Drosophila raised on the same diet as a result of the bacteria that live in their guts, according to a study published this week in Proceedings of the National Academy of Sciences (PNAS).

These apparent mate preferences, which arose after just one generation, suggest that an organism's microbiota can facilitate rapid evolution and speciation.

"It's an interesting paper," said Patty Gowaty of the University of California, Los Angeles, who did not participate in the study. "The thought that these gut bacteria could be associated with the reproductive outcomes for individuals is fascinating."

"There's a lot of emerging research these days about the physiological effects of microbiota, and changes in microbiota in response to environmental conditions," added evolutionary geneticist Paul Hohenlohe of Oregon State University, who was also not involved in the research. "This study ties that into mating preference, too."

Twenty years ago, Diane Dodd of Yale University raised Drosophila melanogaster on different media for more than 25 generations and found that those raised on starch media were more likely to mate with other starch-raised flies, while those raised on maltose were more likely to mate with maltose-raised flies.

"Nobody understood the mechanism for this, but they understood it was important because mating preference is an early stage of sexual isolation and speciation," said microbiologist Eugene Rosenberg, a professor emeritus at Tel Aviv University in Israel and coauthor of the PNAS paper. "And nothing is more fundamental to evolution than the origin of species."

genetic engineering of space travelers


Video - Twilight Zone Episode Third From the Sun

LiveScience | NASA's human spaceflight program might take some giant leaps forward if the agency embraces genetic engineering techniques more fully, according to genomics pioneer J. Craig Venter.

The biologist, who established the J. Craig Venter Institute that created the world's first synthetic organism earlier this year, told a crowd here Saturday (Oct. 30) that human space exploration could benefit from more genetic screening and genetic engineering. Such efforts could help better identify individuals most suited for long space missions, as well as make space travel safer and more efficient, he said.

"I think this could change the shape of what NASA does, if you make the commitment to do it," said Venter, who led a team that decoded the human genome a decade ago. Venter spoke to a group of scientists and engineers who gathered at NASA's Ames Research Center for two different meetings: a synthetic biology workshop put on by NASA, and Space Manufacturing 14: Critical Technologies for Space Settlement, organized by the nonprofit Space Studies Institute.

Astronauts with the right (genetic) stuff

Genetics techniques could come in extremely handy during NASA's astronaut selection process, Venter said. The space agency could screen candidates for certain genes that help make good spaceflyers — once those genes are identified, he added.

Genes that encode robust bone regeneration, for example, would be a plus, helping astronauts on long spaceflights battle the bone loss that is typically a major side effect of living in microgravity. Also a plus for any prospective astronaut: genes that code for rapid repair of DNA, which can be damaged by the high radiation levels in space.

Genetic screening would be a natural extension of what NASA already does — it would just add a level of precision, according to Venter.

"NASA's been doing genetic selection for a long time," he said. "You just don't call it that."

Last summer, the agency chose just nine astronaut candidates — out of a pool of 3,500 — for its rigorous astronaut training program based on a series of established spaceflight requirements and in-depth interviews.

A new microbiome
At some point down the road, NASA could also take advantage of genetic engineering techniques to make long space journeys more efficient and easier on astronauts, Venter said.

As an example, he cited the human microbiome, the teeming mass of microbes that live on and inside every one of us. Every human body hosts about 100 trillion microbes — meaning the bugs outnumber our own cells by a factor of at least 10 to one.

While humans only have about 20,000 genes, our microbiome boasts a collective 10 million or so, Venter said. These microbes provide a lot of services, from helping us digest our food to keeping our immune system's inflammation response from going overboard.

With some tailoring, the microbiome could help us out even more, according to Venter.

"Why not come up with a synthetic microbiome?" he asked.

Theoretically, scientists could engineer gut microbes that help astronauts take up nutrients more efficiently. A synthetic microbiome could also eliminate some pathogens, such as certain bacteria that can cause dental disease. Other tweaks could improve astronauts' living conditions, and perhaps their ability to get along with each other in close quarters.

Body odor is primarily caused by microbes, Venter said. A synthetic microbiome could get rid of the offenders, as well as many gut microbes responsible for excessive sulfur or methane production. Fist tap Nana.

Tuesday, November 02, 2010

democracy's death spiral


Video - ants entered into a terminal circling death spiral.

oftwominds | Democracy's Death Spiral is a positive feedback loop between ever-greater concentrations of wealth and the ever-higher costs of retaining political power.

Positive feedback loops lead to "death spirals" in which destructive forces reinforce each other until the dynamic implodes. One example is an "arms race" in which ever more costly and complex weapons systems must be matched lest one nation in the race fall behind.

Since the number of weapons and their cost are essentially unlimited, then the race continues until one contestant is bankrupted.

Though many would claim it is a simplification, this dynamic was at the root of the Soviet Union's collapse: as the U.S. embarked on a massive expansion of its military and technological power, the Soviet Union exhausted its much smaller resources attempting to keep up.

Though statistics from the Soviet era are not entirely reliable, various scholars have estimated that fully 40% of the Soviet GDP was being expended on its military and military-industrial complex.

The U.S. was spending between 4% and 6% of its GDP on direct military expenditures, even during the height of the Reagan buildup. If you include the Security State (CIA, NSA, et al.), the Veterans Administration and other military-related programs (DARPA, etc.) then the cost was still far less than 10% of GDP.

The greater freedom to exchange information between government-funded research labs, private firms and government-funded universities enabled the U.S. to outdistance the Soviets technologically. Once again a positive feedback loop can be discerned in the way that increased spending on military-related R&D in the U.S. led to increasingly networked nodes of technological advancement which led to greater advances and more spending to develop those technologies.

The U.S. emerged victorious as the sole superpower, but a more closely matched rivalry might have ended with the collapse of both competitors: a Death Spiral of the sort Jared Diamond describes on Easter Island in his book Collapse: How Societies Choose to Fail or Succeed.

In the U.S., the ever-greater concentrations of wealth gathered by an ascendant Financial Power Elite has entered a positive feedback loop with the costs of gaining or retaining political power. The costs of winning an election have skyrocketed to the point that fundraising is the key function of any politico who is not independently extremely wealthy.

This quantum leap up in the costs of gaining or retaining power has forced politicos to curry the favors of those few Elite groups which can give them millions of dollars.

Just as in an arms race, the amounts of money which can be spent on campaigns is essentially unlimited. The explosion of media now requires multi-million dollar campaigns on multiple fronts: broadcast TV, cable TV, mailed flyers, radio spots, promotion campaigns to influence the mainstream media coverage, adverts on the Web and social media campaigns--the list grows longer every year.

Here is the positive feedback loop. Candidate A gains the backing of a Power Elite group (a political action committee or other front) and collects $5 million. As a result of a media blitz, he/she wins.

Between elections, he/she amasses a "war chest" of $5 million from the same donors, guaranteeing that the final cost of the next election will be $10 million.

Potential rivals understand that victory against this well-funded incumbent, no matter how incompetent, will require $15 million. The only sources of that amount of cash are other Financial Power Elites and State-funded fiefdoms like teachers unions, and so each candidate sells their soul to the few "special interests" with deep enough pockets to harvest and contribute millions of dollars.

Now repeat that election cycle a few times and see how quickly the cost rises. The truly pernicious aspect of this positive feedback is this: if wealth wasn't becoming ever more concentrated in the razor-thin slice at the top of the U.S. economy, then politicos couldn't gather huge sums of money from such small groups. They would have to seek a broader base to raise money, and that would dampen the influence of the top donors.

Instead, the cycle grows stronger with each election cycle: to raise the gargantuan sums needed to keep political power, politicos become ever more reliant on a tiny pool of super-wealthy Elites and State-funded fiefdoms.

(In Survival+, I describe the desperate plowing of millions of dollars by public unions and other State-dependent fiefdoms into election campaigns as full spectrum defense of the status quo. When two such fiefdoms are competing for dwindling State resources, I term that Internecine Conflict Between Protected Fiefdoms.)

In other words, the more elections cost, the greater the dependence of politicos on a wealthy Elite. And thus the influence of those Elites over the politicos grows as well. This is how the political machinery of deomocracy gets "captured" by a tiny Financial Power Elite.

corporatist pacs gearing up for 2012

NYTimes | The midterm election campaign will end Tuesday, but one of its most marked developments — the emergence of outside groups, often backed by anonymous donations, that can direct waves of advertising into political battles — is just getting started.

Buoyed by the impact their blistering, anti-Democratic campaigns have had this year, two of the largest new conservative groups helping Republicans are planning to keep pushing their agenda in the lame-duck session of Congress that will begin in two weeks and are already laying the groundwork for a more aggressive campaign in the 2012 presidential race.

That development is causing Democrats to reassess their early financial plans for President Obama’s re-election campaign while forcing them to balance the administration’s demands for more transparency in campaign finance against the pressure for liberal groups to do more to counteract the strength of their conservative counterparts.

Officials with the two conservative groups, American Crossroads and Crossroads GPS — which are on track to spend well over $50 million combined this year, a sizable part of it from undisclosed donors — said they would continue advertising against Democrats as Congress returns, when decisions loom on the extension of the Bush-era tax cuts and immigration.

Robert M. Duncan, the chairman of American Crossroads, which, like Crossroads GPS, was started with help from the Republican strategists Karl Rove and Ed Gillespie, said he also informed major donors late last week that “research and development” was under way to make the groups even more effective in the next election, part of a pitch for continued investment toward a larger goal.

“It’s a bigger prize in 2012, and that’s changing the White House,” Mr. Duncan said. “We’ve planted the flag for permanence, and we believe that we will play a major role for 2012.”

can we save america's crumbling water system?

Infrastructurist | Water infrastructure may not be a sexy topic, but it’s becoming an important one. The American Society of Civil Engineers recently gave America’s drinking-water systems a grade of D-minus. Roughly 10 billion gallons of sewage seep into these crumbling pipes each year. The Obama administration has secured $6 billion for improvements, but the Environmental Protection Agency puts the true cost of fixing water infrastructure at roughly $335 billion. That figure seems staggering until we consider that parts of the country’s water system were built circa the Civil War.

It doesn’t take Abraham Lincoln to see the problem: people have never paid enough for their water, as this public service announcement points out, and they aren’t ready to start now. Attempts to raise utility rates for water systems in several cities across the country have been met with outrage. And because water pipes are out of sight, “no one really understands how bad things have become,” a member of the National Drinking Water Advisory Council told the New York Times in March:

“We’re relying on water systems built by our great-grandparents, and no one wants to pay for the decades we’ve spent ignoring them.”

A recent Newsweek cover story about the world’s water crisis (yes there’s still a Newsweek, for now) reports that some U.S. cities have been forced to privatize their water supplies. The shift enables officials to offload huge maintenance costs while promising jobs. But the colossal nature of water infrastructure lends itself to monopolization, and because water systems are underground they’re difficult for governments to monitor. In fact, Newsweek reports, some cities have grown so dismayed with privatized water that they’ve engaged in costly litigation to cancel the contracts.

The public may finally be ready to shoulder some of the burden. The results of a new survey, released earlier this week by ITT Corporation, suggest that people are willing to pay a little more—just a little—to keep the country’s water pipes from crumbling. (It should be noted that ITT deals in water infrastructure.) While 69 percent of survey respondents agreed that they take their access to clean water for granted, about two-thirds said they would be willing to pay $6.20 more per month to improve their water systems. If applied to all households across the country, such an increase comes to $5.4 billion, ITT notes.

It’s a modest start. Still, any solution requires public officials to confront the problem. So far that hasn’t happened. After all, writes columnist Bob Herbert, fixing America’s water system will take a “maturity and vision and effort and sacrifice” that many public officials seem to lack at the present time when it comes to infrastructure. Point in case, says Herbert:
We can’t even build a railroad tunnel beneath the Hudson River from New Jersey to New York.
Well played, Bob.

Monday, November 01, 2010

james schlesinger - the peak oil debate is over

Dr. James Schlesinger "The Peak Oil Debate is Over" from ASPO-USA on Vimeo.

the spice must flow...,


Video - The Turkmenistan-Afghanistan-Pakistan-India (TAPI) pipeline will be an energy bridge between Central and South Asia.

AsiaTimes | In the Orient, offspring don't rebuke parents, even if the latter are at fault - especially in the post-Soviet space where Marxian formalism continues to prevail as political culture. The sort of stern public rebuke bordering on short shrift that Ashgabat administered to Moscow is extraordinary.

But then, Moscow tested Turkmen patience by trying to create confusion about Ashgabat's policy of positive "neutrality" - building energy bridges to the West alongside its thriving cooperation with Russia and China.

On Thursday, the Turkmen Foreign Ministry bluntly rejected any role for Russia in the proposed Turkmenistan-Afghanistan-Pakistan-India gas pipeline project, commonly known as TAPI. Ashgabat alleged that Moscow is spreading calumnies and expressed the hope that "future statements by Russian officials will be guided by a sense of responsibility and reality".

The reference was to a friendly and seemingly helpful statement by Russian Deputy Prime Minister Igor Sechin (who accompanied President Dmitry Medvedev to the Turkmen capital last weekend) that Russian participation in the TAPI figured in the latest Russian-Turkmen summit talks and "Gazprom may participate in this project in any capacity - builder, designer, participant, etc ... If Gazprom becomes a participant, then we will study possibilities of working in gas sales."

The Turkmen Foreign Ministry said, "Turkmenistan views such statements as an attempt to hamper the normal course of our country's cooperation in the energy sector and call into question its obligations to its partners." It added that there was "no agreement whatsoever" regarding Russian participation in the TAPI.

The TAPI presents a knot of paradoxes and the Russians who hold the pulse of the Central Asian energy scene would have sensed by now that Uncle Sam is close to untying the knot, finally, after a decade-and-a-half of sheer perseverance. The TAPI falls within the first circle of the Caspian great game. When it appears that Russia all but checkmated the United States and the European Union's plans to advance trans-Caspian energy projects bypassing Russia, a thrust appears from the south and east opening up stunning possibilities for the West.

Russia promptly began slouching toward the TAPI - which, incidentally, was originally a Soviet idea but was appropriated by the United States no sooner than the USSR disintegrated - against the backdrop of renewed interest in the project recently among regional powers amid the growing possibility that Afghan peace talks might reconcile the Taliban and that despite the Kashmir problem, Pakistan and India wouldn't mind tangoing.

The TAPI pipeline runs on a roughly 1,600-kilometer route along the ancient Silk Road from Turkmenistan's fabulous Dauletabad gas fields on the Afghan border to Herat in western Afghanistan, then onto Helmand and Kandahar, entering Pakistan's Quetta and turning east toward Multan, and ending up in Fazilka on the Indian side of Pakistan's eastern border. An updated Asian Development Bank (ADB) estimate of 2008 put the project cost for the pipeline with an output of 33 bcm annually at $7.6 billion.

The signals from Ashgabat, Kabul, Islamabad and New Delhi in recent weeks uniformly underscored that the TAPI is in the final stage of take-off. India unambiguously signed up in August. On Wednesday, the Pakistan government gave approval to the project at a cabinet meeting in Islamabad. The ADB is open to financing the project and is expected to be the project's "secretariat".

As things stand, there could be a meeting of the political leaderships of the four participating countries in December to formally kick-start the TAPI.

U.S. Says Genes Should Not Be Eligible for Patents

NYTimes | Reversing a longstanding policy, the federal government said on Friday that human and other genes should not be eligible for patents because they are part of nature. The new position could have a huge impact on medicine and on the biotechnology industry.

The new position was declared in a friend-of-the-court brief filed by the Department of Justice late Friday in a case involving two human genes linked to breast and ovarian cancer.

“We acknowledge that this conclusion is contrary to the longstanding practice of the Patent and Trademark Office, as well as the practice of the National Institutes of Health and other government agencies that have in the past sought and obtained patents for isolated genomic DNA,” the brief said.

It is not clear if the position in the legal brief, which appears to have been the result of discussions among various government agencies, will be put into effect by the Patent Office.

If it were, it is likely to draw protests from some biotechnology companies that say such patents are vital to the development of diagnostic tests, drugs and the emerging field of personalized medicine, in which drugs are tailored for individual patients based on their genes.

“It’s major when the United States, in a filing, reverses decades of policies on an issue that everyone has been focused on for so long,” said Edward Reines, a patent attorney who represents biotechnology companies.

Sunday, October 31, 2010

the checklist manifesto

Gawande | Malcolm Gladwell’s review of The Checklist Manifesto: Over the past decade, through his writing in The New Yorker magazine and his books Complications and Better, Atul Gawande has made a name for himself as a writer of exquisitely crafted meditations on the problems and challenges of modern medicine. His latest book, The Checklist Manifesto, begins on familiar ground, with his experiences as a surgeon. But before long it becomes clear that he is really interested in a problem that afflicts virtually every aspect of the modern world–and that is how professionals deal with the increasing complexity of their responsibilities. It has been years since I read a book so powerful and so thought-provoking.

Gawande begins by making a distinction between errors of ignorance (mistakes we make because we don’t know enough), and errors of ineptitude (mistakes we made because we don’t make proper use of what we know). Failure in the modern world, he writes, is really about the second of these errors, and he walks us through a series of examples from medicine showing how the routine tasks of surgeons have now become so incredibly complicated that mistakes of one kind or another are virtually inevitable: it’s just too easy for an otherwise competent doctor to miss a step, or forget to ask a key question or, in the stress and pressure of the moment, to fail to plan properly for every eventuality. Gawande then visits with pilots and the people who build skyscrapers and comes back with a solution. Experts need checklists–literally–written guides that walk them through the key steps in any complex procedure. In the last section of the book, Gawande shows how his research team has taken this idea, developed a safe surgery checklist, and applied it around the world, with staggering success.

The danger, in a review as short as this, is that it makes Gawande’s book seem narrow in focus or prosaic in its conclusions. It is neither. Gawande is a gorgeous writer and storyteller, and the aims of this book are ambitious. Gawande thinks that the modern world requires us to revisit what we mean by expertise: that experts need help, and that progress depends on experts having the humility to concede that they need help.

peak oil and the healthcare industry


Video - The Peak Oil Threat to Public Health

Bureau of Labor Statistics | Industry organization. About 595,800 establishments make up the healthcare industry; they vary greatly in terms of size, staffing patterns, and organizational structures. About 76 percent of healthcare establishments are offices of physicians, dentists, or other health practitioners. Although hospitals constitute only 1 percent of all healthcare establishments, they employ 35 percent of all workers (table 1).

Table 1. Percent distribution of employment and establishments in health services by detailed industry sector, 2008

Industry segment

Employment

Establishments

Total

100.0

100.0


Ambulatory healthcare services

42.6

87.3

Offices of physicians

17.0

36.0

Home healthcare services

7.2

3.7

Offices of dentists

6.2

20.4

Offices of other health practitioners

4.7

19.6

Outpatient care centers

4.0

3.6

Other ambulatory healthcare services

1.8

1.4

Medical and diagnostic laboratories

1.6

2.4


Hospitals

34.6

1.3

General medical and surgical hospitals

32.5

1.0

Other specialty hospitals

1.4

0.2

Psychiatric and substance abuse hospitals

0.7

0.1


Nursing and residential care facilities

22.8

11.4

Nursing care facilities

12.2

2.8

Community care facilities for the elderly

5.2

3.5

Residential mental health facilities

4.1

4.0

Other residential care facilities

1.3

1.1

SOURCE: BLS Quarterly Census of Employment and Wages, 2008.

The healthcare industry includes establishments ranging from small-town private practices of physicians who employ only one medical assistant to busy inner-city hospitals that provide thousands of diverse jobs. In 2008, around 48 percent of non-hospital healthcare establishments employed fewer than five workers. In contrast, 72 percent of hospital employees were in establishments with more than 1,000 workers.

The healthcare industry consists of the following segments:

Hospitals. Hospitals provide complete medical care, ranging from diagnostic services, to surgery, to continuous nursing care. Some hospitals specialize in treatment of the mentally ill, cancer patients, or children. Hospital-based care may be on an inpatient (overnight) or outpatient basis. The mix of workers needed varies, depending on the size, geographic location, goals, philosophy, funding, organization, and management style of the institution. As hospitals work to improve efficiency, care continues to shift from an inpatient to outpatient basis whenever possible.

Nursing and residential care facilities. Nursing care facilities provide inpatient nursing, rehabilitation, and health-related personal care to those who need continuous nursing care, but do not require hospital services. Nursing aides provide the vast majority of direct care. Other facilities, such as convalescent homes, help patients who need less assistance. Residential care facilities provide around-the-clock social and personal care to children, the elderly, and others who have limited ability to care for themselves. Workers care for residents of assisted-living facilities, alcohol and drug rehabilitation centers, group homes, and halfway houses. Nursing and medical care, however, are not the main functions of establishments providing residential care, as they are in nursing care facilities.

Offices of physicians. About 36 percent of all healthcare establishments fall into this industry segment. Physicians and surgeons practice privately or in groups of practitioners who have the same or different specialties. Many physicians and surgeons prefer to join group practices because they afford backup coverage, reduce overhead expenses, and facilitate consultation with peers. Physicians and surgeons are increasingly working as salaried employees of group medical practices, clinics, or integrated health systems.

Offices of dentists. About 20 percent of healthcare establishments are dentist's offices. Most employ only a few workers, who provide preventative, cosmetic, or emergency care. Some offices specialize in a single field of dentistry, such as orthodontics or periodontics.

Home healthcare services.
Skilled nursing or medical care is sometimes provided in the home, under a physician's supervision. Home healthcare services are provided mainly to the elderly. The development of in-home medical technologies, substantial cost savings, and patients' preference for care in the home have helped change this once-small segment of the industry into one of the fastest growing healthcare services.

Offices of other health practitioners.
This segment of the industry includes the offices of chiropractors, optometrists, podiatrists, occupational and physical therapists, psychologists, audiologists, speech-language pathologists, dietitians, and other health practitioners. Demand for the services of this segment is related to the ability of patients to pay, either directly or through health insurance. Hospitals and nursing facilities may contract out for these services. This segment also includes the offices of practitioners of alternative medicine, such as acupuncturists, homeopaths, hypnotherapists, and naturopaths.

Ambulatory healthcare services. This segment includes outpatient care center and medical and diagnostic laboratories. These establishments are diverse including kidney dialysis centers, outpatient mental health and substance abuse centers, blood and organ banks, and medical labs that analyze blood, do diagnostic imaging, and perform other clinical tests.

Recent developments. In the rapidly changing healthcare industry, technological advances have made many new procedures and methods of diagnosis and treatment possible. Clinical developments, such as infection control, less invasive surgical techniques, advances in reproductive technology, and gene therapy for cancer treatment, continue to increase the longevity and improve the quality of life of many Americans. Advances in medical technology also have improved the survival rates of trauma victims and the severely ill, who need extensive care from therapists and social workers as well as other support personnel.

In addition, advances in information technology have a perceived improvement on patient care and worker efficiency. Devices such as hand-held computers are used record a patient’s medical history. Information on vital signs and orders for tests are transferred electronically to a main database; this process eliminates the need for paper and reduces recordkeeping errors. Adoption of electronic health records is, however, relatively low presently.

Cost containment also is shaping the healthcare industry, as shown by the growing emphasis on providing services on an outpatient, ambulatory basis; limiting unnecessary or low-priority services; and stressing preventive care, which reduces the potential cost of undiagnosed, untreated medical conditions. Enrollment in managed care programs—predominantly preferred provider organizations, health maintenance organizations, and hybrid plans such as point-of-service programs—continues to grow. These prepaid plans provide comprehensive coverage to members and control health insurance costs by emphasizing preventive care. Cost effectiveness also is improved with the increased use of integrated delivery systems, which combine two or more segments of the industry to increase efficiency through the streamlining of functions, primarily financial and managerial. These changes will continue to reshape not only the nature of the healthcare workforce, but also the manner in which healthcare is provided.

Various healthcare reforms are presently under consideration. These reforms may affect the number of people covered by some form of health insurance, the number of people being treated by healthcare providers, and the number and type of healthcare procedures that will be performed.

crapped out....,

HuffPo | It's been a long, hard fall for Las Vegas.

With an economy tied to consumer spending and the housing industry, Sin City region has gone from one of America's bright spots to one of its most troubled. The Las Vegas area is among the most economically stressed in the country, according to the Associated Press's monthly ranking.

Fully 15 percent of Las Vegas residents -- or a total of 145,000 people -- are unemployed, a local record. (Nationally, the unemployment rate has held steady at 9.6 percent.) On the state level, as HuffPost's Arthur Delaney and Ryan Grim reported in July, there is no greater concentration of economic woe than in Nevada. Factoring in the underemployed and those who have given up looking for work, Nevada's true unemployment rate may be 20 percent, according to the Las Vegas Review-Journal.

In the state's flagship city, however, the housing boom and job crisis have created more than a few veritable ghost towns and have stalled large developments on the Las Vegas Strip.

Getty photographers Spencer Platt and Ethan Miller recently captured some of the most haunting images of the new, recession-addled Las Vegas landscape.

Saturday, October 30, 2010

Is this happening in afghanistan? If not, why not? If not, when?

Truthteller | Our army that now remains in Vietnam is in a state approaching collapse, with individual units avoiding or having refused combat, murdering their officers and noncommissioned officers, drug-ridden, and dispirited where not near-mutinous Conditions exist among American forces in Vietnam that have only been exceeded in this century by…the collapse of the Tsarist armies in 1916 and 1917.
Armed Forces Journal, June 1971
The most neglected aspect of the Vietnam War is the soldiers’ revolt–the mass upheaval from below that unraveled the American army. It is a great reality check in an era when the U.S. touts itself as an invincible nation. For this reason, the soldiers’ revolt has been written out of official history.

The army revolt pitted enlisted soldiers against officers who viewed them as expendable. Liberal academics have reduced the radicalism of the 1960s to middle-class concerns and activities, while ignoring military rebellion. But the militancy of the 1960s began with the Black liberation struggle, and it reached its climax with the unity of White and Black soldiers.

washington rules - america's path to permanent war

AsiaTimes | Washington Rules aims to take stock of conventional wisdom in its most influential and enduring form, namely the package of assumptions, habits, and precepts that have defined the tradition of statecraft to which the United States has adhered since the end of World War II - the era of global dominance now drawing to a close. This postwar tradition combines two components, each one so deeply embedded in the American collective consciousness as to have all but disappeared from view.

The first component specifies norms according to which the international order ought to work and charges the United States with responsibility for enforcing those norms. Call this the American credo. In the simplest terms, the credo summons the United States - and the United States alone - to lead, save, liberate, and ultimately transform the world. In a celebrated manifesto issued at the dawn of what he termed "The American Century", Henry R Luce made the case for this spacious conception of global leadership. Writing in Life magazine in early 1941, the influential publisher exhorted his fellow citizens to "accept wholeheartedly our duty to exert upon the world the full impact of our influence for such purposes as we see fit and by such means as we see fit". Luce thereby captured what remains even today the credo's essence.

Luce's concept of an American Century, an age of unquestioned American global primacy, resonated, especially in Washington. His evocative phrase found a permanent place in the lexicon of national politics. (Recall that the neoconservatives who, in the 1990s, lobbied for more militant policies, named their enterprise the Project for a New American Century.) So, too, did Luce's expansive claim of prerogatives to be exercised by the United States. Even today, whenever public figures allude to America's responsibility to lead, they signal their fidelity to this creed. Along with respectful allusions to God and "the troops," adherence to Luce's credo has become a de facto prerequisite for high office. Question its claims and your prospects of being heard in the hubbub of national politics become nil.

Note, however, that the duty Luce ascribed to Americans has two components. It is not only up to Americans, he wrote, to choose the purposes for which they would bring their influence to bear, but to choose the means as well. Here we confront the second component of the postwar tradition of American statecraft.

With regard to means, that tradition has emphasized activism over example, hard power over soft, and coercion (often styled "negotiating from a position of strength") over suasion. Above all, the exercise of global leadership as prescribed by the credo obliges the United States to maintain military capabilities staggeringly in excess of those required for self-defense. Prior to World War II, Americans by and large viewed military power and institutions with skepticism, if not outright hostility. In the wake of World War II, that changed. An affinity for military might emerged as central to the American identity.

By the midpoint of the 20th century, "the Pentagon" had ceased to be merely a gigantic five-sided building. Like "Wall Street" at the end of the 19th century, it had become Leviathan, its actions veiled in secrecy, its reach extending around the world. Yet while the concentration of power in Wall Street had once evoked deep fear and suspicion, Americans by and large saw the concentration of power in the Pentagon as benign. Most found it reassuring.

A people who had long seen standing armies as a threat to liberty now came to believe that the preservation of liberty required them to lavish resources on the armed forces. During the Cold War, Americans worried ceaselessly about falling behind the Russians, even though the Pentagon consistently maintained a position of overall primacy. Once the Soviet threat disappeared, mere primacy no longer sufficed. With barely a whisper of national debate, unambiguous and perpetual global military supremacy emerged as an essential predicate to global leadership.

george soros - why I support legal marijuana


Video - Financial News Network George Soros give $1 Million to support Cali Prop 19.

WSJ | Our marijuana laws are clearly doing more harm than good. The criminalization of marijuana did not prevent marijuana from becoming the most widely used illegal substance in the United States and many other countries. But it did result in extensive costs and negative consequences.

Law enforcement agencies today spend many billions of taxpayer dollars annually trying to enforce this unenforceable prohibition. The roughly 750,000 arrests they make each year for possession of small amounts of marijuana represent more than 40% of all drug arrests.

Regulating and taxing marijuana would simultaneously save taxpayers billions of dollars in enforcement and incarceration costs, while providing many billions of dollars in revenue annually. It also would reduce the crime, violence and corruption associated with drug markets, and the violations of civil liberties and human rights that occur when large numbers of otherwise law-abiding citizens are subject to arrest. Police could focus on serious crime instead.

The racial inequities that are part and parcel of marijuana enforcement policies cannot be ignored. African-Americans are no more likely than other Americans to use marijuana but they are three, five or even 10 times more likely—depending on the city—to be arrested for possessing marijuana. I agree with Alice Huffman, president of the California NAACP, when she says that being caught up in the criminal justice system does more harm to young people than marijuana itself. Giving millions of young Americans a permanent drug arrest record that may follow them for life serves no one's interests.

Racial prejudice also helps explain the origins of marijuana prohibition. When California and other U.S. states first decided (between 1915 and 1933) to criminalize marijuana, the principal motivations were not grounded in science or public health but rather in prejudice and discrimination against immigrants from Mexico who reputedly smoked the "killer weed."

Who most benefits from keeping marijuana illegal? The greatest beneficiaries are the major criminal organizations in Mexico and elsewhere that earn billions of dollars annually from this illicit trade—and who would rapidly lose their competitive advantage if marijuana were a legal commodity. Some claim that they would only move into other illicit enterprises, but they are more likely to be weakened by being deprived of the easy profits they can earn with marijuana.

This was just one reason the Latin American Commission on Drugs and Democracy—chaired by three distinguished former presidents, Fernando Henrique Cardoso of Brazil, César Gaviria of Colombia and Ernesto Zedillo of Mexico—included marijuana decriminalization among their recommendations for reforming drug policies in the Americas.

strong immunity=low fertility

The Scientist | A study in wild sheep may help explain why natural selection has not eradicated weak or self-destructive immune systems. A fluctuating trade-off between reproduction and survival in a feral population of Soay sheep may resolve the age-old question of why natural selection has failed to eradicate genes for both infection-prone and self-assailing immune systems.

The potential answer, published in Science this week (29th October), comes from the nascent field of ecoimmunology, which examines how different levels of antibodies in the blood of wild animals can influence their ability to survive and produce young.

Specifically, the authors found that, among a population of isolated, wild sheep, individuals with higher levels of antibodies associated with autoimmunity in other species were more likely to survive harsh weather conditions, but also reproduced less. Consequently, the benefits of high immunity, such as quick and efficient riddance of infection, may come with a cost -- less energy for reproduction.

"This paper reveals that more [antibodies] might not always be better, and that to understand the evolution of immune systems, it will be critical to study them in free-living, outbred organisms," Lynn Martin, an ecoimmunologist at the University of South Florida, who was not affiliated with the study, said in an email to The Scientist.

Friday, October 29, 2010

why some psychopaths are in leadership positions


A Clockwork Orange - Droog Fight

Psychology Today | It is well observed that psychopaths (a.k.a. sociopaths) are found both in prison and in managerial positions. In "The Sociopath Next Door," Martha Stout analyzed many individuals with psychopathy and most of them were not part of the offender population. I think that leadership researchers have somehow overlooked these types of "leaders" or organizational psychopaths who have inflicted pain to many but succeeded in maintaining their positions (even been promoted).

Robert Hare's Psychopathy Checklist-Revised (PCL-R, 2nd ed.) suggests that psychopathy consists of the following traits:
(1) interpersonal or affective defects (e.g., glibness or superficial charm, grandiose feelings of self-worth, conning or manipulative behavior, lack of remorse or guilt, shallow affects, callousness or lack of empathy)
(2) social deviance and antisocial (irresponsibility, parasitic lifestyle, impulsivity, and unstable relationships, criminal versatility).
(3) other attributes.
However, this inventory is apparently intended only for the forensic population and not for psychopaths who know how to elude the criminal justice system.

how psychopaths choose their victims

Psychology Today | As my fellow Psychology Today blogger Marisa Mauro has pointed out, psychologists have long been known that the more psychopathic a person is, the more easily they can identify potential victims. Indeed, they can do so just by watching the way a person moves. In one study, test subjects watched videos of twelve individuals walking, shot from behind, and rated how easily they could be mugged. As it happened, some of the people in the videotapes really had been mugged -- and the most psychopathic of the subjects were able to tell which was which. Writes Mauro:

The [subjects] completed the Self-Report Psychopathy Scale: Version III, which measures interpersonal and affective traits associated with psychopathy as well as intra-personal instability and antisocial traits... Overall results confirmed a strong positive correlation between psychopathy scores and accuracy of victim identification. This means that individuals that score higher for psychopathy are better at selecting victims.

And what was it about these people that made them seem vulnerable? A later study found that the men were picking up on whole suite of nonverbal cues, including the length of their stride, how they shifted their weight, and how high they lifted their feet. Taken together, these cues gave the psychopathic men a rough gauge of how confident their potential victims were. Body language that implies a lack of confidence --- read: socially submissive --- includes lack of eye contact, fidgeting of the hands and feet, and the avoidance of large gestures when shifting posture.

The researchers' findings confirmed my own suspicions regarding the dubious fellow I mentioned above. The women who wound up on the receiving end of his attentions were individuals who, in their own description, were not very worldly, experienced, or outgoing. They were psychologically vulnerable and hence ill-equipped to either resist this fellow's predations or to deal with them emotionally after they had occurred. In the aftermath, they are so traumatized that even speaking about their experiences is extremely painful. And so the psychopath continues on his way. Fist tap Dale.

is there a liberal gene?

Discovery | Is political ideology derived from a person's social environment or is it a result of genetic predisposition?

It's an interaction of both, according to a recent study on our political leanings that boosts both sides of the nature versus nurture debate.

Scientists at the University of California San Diego and Harvard University determined that people who carry a variant of the DRD4 gene are more likely to be liberals as adults, depending on the number of friendships they had during high school. They published their study in a recent issue of The Journal of Politics.

Data was analyzed from the National Longitudinal Study of Adolescent Health (the same source for a recent study that found intelligent children drink more alcohol as adults).

The four authors, including UCSD's James Fowler, wanted to explore if politics were heritable by identifying a specific gene variant associated with political leaning. They hypothesized that individuals with a genetic predisposition toward seeking out new experiences would tend to be more liberal.

The 7R variant of DRD4, a dopamine receptor gene, had previously been associated with novelty seeking. The researchers theorized novelty seeking would be related to openness, a psychological trait that has been associated with political liberalism.

However, social environment was critical. The more friends gene carriers have in high school, the more likely they are to be liberals as adults. The authors write, "Ten friends can move a person with two copies of 7R allele almost halfway from being a conservative to moderate or from being moderate to liberal."

They theorize a larger social network may bring more diverse viewpoints, which could be an influence on the liberal development.

Neither the gene nor social networks alone influenced political identification. Fist tap Ken.

Thursday, October 28, 2010

america 2.0 - from private greed to public service

how NOT to organize a community

ClubOrlov | Dire predictions made by authoritative figures can provide the impetus to attempt great things: establish community gardens and farmer's markets, lobby for improved public transportation, bike lanes and sidewalks, promote ride-sharing initiatives, weatherize existing homes and impose more stringent construction standards for new ones, construct of windmill farms and install solar panels on public buildings, promote the use of composting toilets and high-efficiency lighting and so on. In the midst of all this organizational activity neighbors get a chance to meet, perhaps for the first time, and discover a commonality of interests that leads them to form acquaintances and perhaps even friendships. As neighbors get to know each other, they start looking out for each other, improving safety and reducing crime. As the community becomes more tight-knit, it changes in atmosphere and appearance, becoming more fashionable and desirable, attracting better-educated and more prosperous residents while pricing out the undesirable element. News of these vast improvements spreads far and wide, and the community becomes a tourist mecca, complete with food festivals, swank boutiques and pricy bric-à-brac shops and restaurants.

The undesirable element is forced to decamp to a less desirable neighborhood nearby. There, it has no choice but to suffer with high levels of crime, but is typically afraid to ask the police for help, having learned from experience that the police are more likely to harass them then to help them, to arrest them for minor offenses and to round them up and deport them if they happen to be illegal immigrants. They also learn to be careful around members of local gangs and drug dealers. Since official jobs in the neighborhood are scarce, they seek informal, cash-based employment, contributing to an underground economy. Seeking safety in numbers, they self-organize along racial and ethnic lines, and, to promote their common interests, form ethnic mafias that strive to dominate one or more forms of illegal or semi-legal activity. Growing up in a dangerous, violent environment, their children become tough at a young age, and, those that survive, develop excellent situational awareness that allows them to steer clear of dangerous situations and to know when to resort to violence.

When the fossil fuel-based national economy shuts down due to the increasingly well understood local ramifications of the global phenomenon of Peak Oil, both of these communities are harmed, but to different extents and in different ways.

Fuck Robert Kagan And Would He Please Now Just Go Quietly Burn In Hell?

politico | The Washington Post on Friday announced it will no longer endorse presidential candidates, breaking decades of tradition in a...