reported cases in ukraine double in two days

Recombinomics | Update: The numbers from the latest update from Ukraine (see map) continue to alarm. More than half of the Oblasts and cities listed exceed the epidemic threshold, including Kiev and Kiev Oblast, raising concerns that the increase in case numbers will accelerate. Moreover, hospitalization of 39,603 raises concerns that the number of deaths will also accelerate, since 11% of hospitalized cases in California died.

478,456 Influenza/ARI

24,003 Hospitalized

60 Ventilators

81 Deaths

The above numbers are from the latest update from Ukraine. The number of infected patients has almost doubled to just under ½ million, compared to the report two days ago (see map). Hospitalized patients also have spiked higher, to 24K from 15K. ICU cases are not listed, but 60 on ventilators are. However, most (37) of those on ventilators are Chernivisti Oblast, but Lviv, which has the most fatalities and cases, has none, suggesting the data is incomplete or there are significant shortages of ventilators. The number of dead has risen to 81, but media reports describe additional fatalities, include those in the Kiev Oblast.

The explosion of cases again raises concerns that the number of fatalities is significantly higher than the 81 listed. Media reports have described an equal number of pneumonia fatalities which were not considered flu related. The basis of these exclusions remains unclear. Similarly, anecdotal reports suggest the number of fatalities is markedly higher than the 81 in the table.

The rapid rise in reported infections, hospitalizations, and deaths in the past few days raise concerns that the virus is transmitting very efficiently. Spikes in cases have been reported throughout the northern hemisphere, but the spike in fatalities and the frequency in hemorrhagic cases in Ukraine have raised concerns.

Earlier media reports suggest that an update by WHO might be issued today and include preliminary analysis of samples sent to Mill Hill in London.

Daily updates on the rapidly evolving situation in Ukraine, including sequence analysis, would be useful.

sista dr. teresa forcades drops knowledge on the flu

unidentified flue outbreak in western ukraine

Zik | Western Ukraine was hit by a severe epidemic of unidentified influenza, tentatively diagnosed by doctors as viral pneumonia. The number of dead has climbed dramatically. Doctors advise Western Ukrainians to stay at home and use preventive medication. The first pedestrians wearing face masks have been seen on Lviv streetsTwo of the dead patients were in the 22-35 age group, with 2 others over 60. He diagnosed the disease as viral pneumonia.

“We have sent the analyses to Kyiv. We don’t believe it’s the swine flue. Neither do we know what kind of pneumonia it is,
Borysevych stressed. Viral tests can last from one to two weeks. They are complicated and not done in Lviv. The course of the disease was very quick. The symptoms included very high temperature and short-wind cough.

The disease started as an ordinary chill with headache and temperature. The symptoms lasted for a week before patient condition began to aggravate.

Zakarpattya Oblast
A man has died from the swine flue in Volovets. He has recently returned from Saint Petersburg, Russia, suffering from a cold. He was rushed to the hospital when pneumonia symptoms were found by doctors. Another local who came from Moscow became sick and went to see his doctor in time. Now he is recovering safely.

Ivano-Frankivsk Oblast
All the six dead young people had symptoms of severe hemmorhagic pneumonia. The disease starts slowly, with temperature rising to 37.2 – 37.3 degrees, slight cough and pain in joints. Nasal catarrh developed at the end of the second or third day. Autopsy revealed that the lungs were soaked with blood, the oblast chief specialist said.

Chernivtsi Oblast
The number of persons with common flue in Chernivtsi has grown from 2,623 to 4,053. According to the local medical authorities, the city has been hit by an unknown type of the flue. The tests to identify the virus will be ready only in 2 weeks, doctors say.

nanoparticles hazardous to dna

The Scientist | Nanoparticles can damage DNA even in cells that are not directly exposed to them, according to an in vitro study published online today (November 5) in Nature Nanotechnology -- raising further questions about the safety of nanomaterials used in clinical therapies.

"DNA damage due to nanoparticles has been described for many types of nanoparticles, but that's done in a primary or direct sense," said Andre Nel, chief of NanoMedicine at the University of California, Los Angeles, who was not involved in the study. "Indirect DNA damage to hazardous nanoparticles is not something that I have seen described before."

Scientists are using nanotechnology to develop delivery systems for drugs and imaging agents, but some studies have suggested these particles may be toxic. Researchers have linked inhalation of nanoparticles or nanotubes to cardoirespiratory disease, for example. Additionally, nanoparticle debris from implants, such as cobalt-chromium (CoCr) alloy particles which can be released from metal-on-metal orthopedic joint replacements, are known to damage human cells in culture.

clusters of hemorrhagic H1N1 pneumonia in ukraine

Recombinomics | All the six dead young people had symptoms of severe hemmorhagic pneumonia. The disease starts slowly, with temperature rising to 37.2 - 37.3 degrees, slight cough and pain in joints. Nasal catarrh developed at the end of the second or third day. Autopsy revealed that the lungs were soaked with blood, the oblast chief specialist said.

The above comments are from an early story describing cases in Ukraine. The clustering of hemorrhagic cases raised concerns. The concern was increased by anecdotal reports citing a high frequency of such cases in Lviv (see map). The recent WHO announcement that they were initially focusing of severe acute respiratory illness in Lviv also increased concerns.

Hemorrhagic pneumonia was also observed in the 1918 pandemic and was thought to be linked to cytokine storm. Consequently, those with robust immune systems (previously health young adults) disproportionately died, which has also been seen in the current outbreak (Mexico, US, and worldwide). However, the cases in Ukraine appear to be clustered, raising concerns that the virus has changed.

However, the change may be minor, since the current H1N1 has produced the above symptoms in earlier cases. More severe cases may be linked to a higher viral load, which could be linked to minor genetic changes, or simply due to concentration of virus in schools. In the US the spread of the virus has been linked to school openings, which lead to an explosion of cases and subsequent student deaths. However, now there are increases in fatalities in teachers and administrators, increasing concerns worldwide.

In Ukraine, weather changes and heating issues may have led to a surge in cases, and increased concentrations of virus could have produced conditions favoring high viral loads and increased cytokine storms.

the strange case of joseph moshe

HuffPo | A man suspected of making threats against the White House was pulled from his car Thursday after an hours-long standoff in the parking lot of the Federal Building in West Los Angeles.

The man had refused to leave his red Volkswagen Beetle and withstood four rounds of chemical agents tossed inside the car after police broke a rear window. About an hour later, officers shot out the drivers window with a bean bag gun and pulled him out.

Secret Service spokesman Ed Donovan identified the suspect as Joseph Moshe, 56, of Los Angeles. Moshe is suspected of calling a police dispatch number Wednesday and making threatening statements about the White House, Donovan said.

(but that's not the interesting part)

The interesting part is in the comments below the article about this arrest;

Project Camelot and Bill Deagle reported another side of this story involving Joseph Moshe, a biological­-scientist with a dual citizenship in Israel and mussad traning in biological warfare, hence his ability to withstand the tear gas attack. Moshe phoned Dr. Tru Ott's radio show and said that he had evidence that the vaccine company Baxter was making a bioweapon that would cause a plague when the vaccine was released.

The day after Moshe phoned the radio show, a swat team surrounded his Volkswagen Beetle near the Federal building near the Israeli consulate which was apparently Moshes destination. The mainstream media spun a story that Moshe had threatened the White House with a bomb, that there were outstanding warrants against him and that he was depressed. No mention of that Moshe was a biological­-scientist or the information he provided on Dr. True Otts radio show about the vaccine company Baxter.

NBC LA reported on Aug 17 that Moshe was in jail but Dr. Deagle says that Moshe has been sent to Israel.

The would-be bomber, Joseph Moshe, called into the Dr True Ott Show on Republic Broadcasting and said he was a microbiologist who wanted to hand over evidence to a States Attorney regarding tainted H1N1 vaccines being produced by Baxter pharmaceutical. He claimed that that Baxter’s lab in the Ukraine was in fact preparing a bioweapon disguised as a vaccine. He maintained that the vaccine contained both adjuvants designed to weaken the immune system, and replicated RNA from the virus responsible for the 1918 global pandemic. That’s it. He made no threat against Obama, nor said anything about bombs or any attack. The following day he was hauled out of his red VW beetle by a SWAT team and arrested. He was immediately extradited to Israel, where he has dual-citizenship, and hasn’t been heard from since. All this talk portraying him as being a right-wing nutcase is disinformation designed to keep his disturbing comments from alarming the public.

Read the extended commentary that accompanies this youtube video of the arrest of Moshe.

policy and technology - conflict or synergy?

UCTV | A highlight of this year's Energy Summit was the Town-Hall Meeting where audience members engaged in a dialogue with energy experts Randy Komisar, Arun Majumdar and Michael McQuade who touched mainly on consumer behavior, energy investment strategies, future energy outlook, and broadly on social responsibility of energy efficiency.

technology, politics, and the economics of reduced energy consumption

UCTV | Lynn Scarlett, former Deputy Secretary of the Interior, argues that investing in nature's capital is a smart twenty-first century energy policy. Arun Majumdar, Lawrence Berkeley Lab, explores how regulation and technology can work together to improve energy consumption. He also looks at some of the new technologies that may become large-scale solutions.

science for energy efficient production and use

UCTV | Raymond Orbach, former Under Secretary for Science, United States Department of Energy, argues that the three major energy challenges in the US are energy security, environmental sustainability, and economic impact and that a unique opportunity has emerged to change the world using a new ability to alter materials at the atomic scale like never before possible.

suncatcher

in the muck

The Scientist | Duckweed first appeared in satellite images of Venezuela in 2004 as a mysterious swirl of green on the surface of Lake Marcaibo, doubling in size with each passing day. Marcaibo is one of South America’s largest bodies of water, but with brackish water and few nutrients, it had never harbored this rapid-growing aquatic plant. Local scientists speculated that heavy rains washed sewage and nutrients into the lake along with duckweed colonies from neighboring ponds. By June, they estimated that the world’s smallest flowering plant covered 18 percent of the lake’s surface before it began receding.

The invasion could have been an ecological disaster, but for Rutgers geneticist Randall Kerstetter, it was a sign of hope. In the taxonomic showdown over the ideal organism for producing biofuel, Kerstetter is putting his mental energy into duckweed. “Duckweed is the fastest growing plant,” he says. “If you’re interested in biofuels, you’re interested in biomass.”

tiny tubers

The Scientist | When Ros Gleadow opened the airlock to the greenhouse at The Australian National University, she stepped into the atmosphere of the future. The air was thick with carbon dioxide—700 parts per million, to be precise—which matches the concentration predicted 90 years from now. While evaluating the responses of crops to the altered atmosphere in the summer of 2008, she found that the cotton, sorghum, soybean and cassava plants she’d planted 9 months earlier grew higher, a little woodier, and with more stems and smaller leaves than normal—all of which she’d expected. But when she dug the cassavas out of their pots, the tubers, which usually grow as large as yams, looked like stunted fingers.

Her cassavas of the future had produced 80 percent less food. “It came completely unexpectedly because plants normally grow bigger under higher CO2,” says Gleadow, a plant physiologist at Monash University in Melbourne. Her immediate thought went to the millions of people living in the tropics, where cassava is the third largest source of dietary carbohydrates. “If the yield decreases, there’s going to be a lot of hungry people.”

That wasn’t the only problem. The cassava plants themselves had become poisonous. Like 60 percent of all our staple crops, cassava produces chemicals called cyanogenic glycosides to deter grazing animals, which, when chewed, release cyanide gas. In small quantities, the cyanide tastes like bitter cherries, enough to ward off animals. But the high-CO2 cassavas produced three times the cyanide of today’s plant. (The poison largely shows up in the leaves, which most people avoid, although some in African countries eat the leaves as a protein supplement.) Gleadow hypothesizes that her cassavas may have poisoned themselves, meaning the extra cyanide shrank the tubers (Plant Biology, published online August 6, 2009).

Until recently, modelers saw CO2’s effect on plant life as the silver lining of climate change. They thought increases in the gas would act as fertilizer, making crops grow bigger and more lush. After all, CO2 is one of the main components of photosynthesis. In the late 1980s, experimenters projected as much as 30 percent increases by 2050 in yield for staples like wheat and soy. But recent experiments under open-air conditions showed half that rate of growth (Science, 312: 1918–21, 2006).

buffett buys bnsf...,

Washington Post | The biggest name in investing is making what he calls an "all-in wager" on the U.S. economy - $34 billion to own a railroad that hauls everything from corn to cars across the country.

The acquisition of Burlington Northern Santa Fe, the nation's second-largest railroad, would be the biggest ever for Warren Buffett's Berkshire Hathaway investment company.

It's a natural fit for the Oracle of Omaha, a city with a special place in railroad history. It was the starting point for the westward push of the transcontinental railroad. Today, Omaha is the headquarters of Union Pacific, and BNSF trains rumble through every day.

In a statement, Buffett, whose investing decisions are carefully scrutinized by the world of finance, voiced confidence in the railroad industry.

"Most important of all, however, it's an all-in wager on the economic future of the United States. I love these bets," he said Tuesday.

inside lsd - tonight

National Geographic | LSDs inventor Albert Hofmann called it "medicine for the soul." The Beatles wrote songs about it. Secret military mind control experiments exploited its hallucinogenic powers. Outlawed in 1966, LSD became a street drug and developed a reputation as the dangerous toy of the counterculture, capable of inspiring either moments of genius, or a descent into madness. Now science is taking a fresh look at LSD, including the first human trials in over 35 years. Using enhanced brain imaging, non-hallucinogenic versions of the drug and information from an underground network of test subjects who suffer from an agonizing condition for which there is no cure, researchers are finding that this "trippy" drug could become the pharmaceutical of the future. Can it enhance our brain power, expand our creativity and cure disease? To find out, Explorer puts LSD under the microscope.

foxes and chicken coops

HuffPo | There have been a few financial insiders who've raised an eyebrow over Storch's hire. Zero Hedge pointed to a big flaw in Storch's background "...at least the SEC could have hired someone with actual market/broker experience. Based on his record, Mr. Storch is not even a licensed (Series 7/63) broker."

The Atlantic points to some real concerns about his level of experience: "I'm not sure what's scarier, that this guy worked at an investment bank that many believe has questionable ethics and too cozy a Washington connection, or that he's just 29. His 'great deal of background' must be those seven long years since college ended."

For those who've lamented the various links between Goldman Sachs and the financial regulatory system, this certainly isn't good news.

Bloomberg reports that the Securities Exchange Commission has named Adam Storch, a former Goldman exec, as its enforcement division's first chief operating officer. Storch is actually just 29 years old and previously worked in Goldman's business intelligence unit.

Here's Bloomberg:

"The COO, who started Oct. 13, has "a great deal of background" in technology and managing processes and the pace of work, Robert Khuzami, head of enforcement, said yesterday in Washington. Storch, who worked since 2004 in a unit at Goldman Sachs that reviewed contracts and transactions for signs of fraud, will be charged with making the unit more efficient. Storch, reached by telephone at the SEC, declined to comment."

According to what appears to be his LinkedIn profile, Storch spent his undergraduate years at the State University Of New York At Buffalo, and earned an MBA from New York University's Stern School Of Business. Other experience -- besides Goldman -- includes working as a Senior Analyst at Deloitte and Touche.

smooth criminals

Neurological Correlates | New journal volume on “Biosocial Criminality” and two reports selected: One, because psychopaths use murder more as an instrumentality than as an expression of emotion, they don’t tell anyone about their crimes, and, moreover, therefore, are brought up on lesser offenses and get out earlier (my interpretation). Two, psychopaths can see vulnerability in others by the way they walk. Fist tap Dale.

militarism and extremism

teach your teachers well....,

NYTimes | ARNE DUNCAN, the secretary of education, recently called for sweeping changes to the way we select and train teachers. He’s right. If we really want good schools, we need to create a critical mass of great teachers. And if we want smart, passionate people to become these great educators, we have to attract them with excellent programs and train them properly in the substance and practice of teaching.

Our best universities have, paradoxically, typically looked down their noses at education, as if it were intellectually inferior. The result is that the strongest students are often in colleges that have no interest in education, while the most inspiring professors aren’t working with students who want to teach. This means that comparatively weaker students in less intellectually rigorous programs are the ones preparing to become teachers.

So the first step is to get the best colleges to throw themselves into the fray. If education was a good enough topic for Plato, John Dewey and William James, it should be good enough for 21st-century college professors.

These new teacher programs should be selective, requiring a 3.5 undergraduate grade point average and an intensive application process. But they should also be free of charge, and admission should include a stipend for the first three years of teaching in a public school.

schools are where stimulus saved jobs

NYTimes | The best symbol of the $787 billion federal stimulus program turns out not to be a construction worker in a hard hat, but rather a classroom teacher saved from a layoff.

On Friday, the Obama administration released the most detailed information yet on the jobs created by the stimulus. Of the 640,239 jobs recipients claimed to have created or saved so far, officials said, more than half — 325,000 — were in education. Most were teachers’ jobs that states said were saved when stimulus money averted a need for layoffs.

Although the stimulus was initially sold in large part as a public works program, only about 80,000 of the jobs that were claimed Friday were in construction.

Of course, counting jobs that were saved can be a squishier proposition than counting jobs that were created. Teachers have been laid off in some areas — and budget officials say that there would have been more layoffs without the stimulus money — but it is difficult to say with certainty how many teachers would have been laid off without that money.

Indiana, for example, reported saving or creating 13,232 education jobs with its stimulus money, but Cris Johnston, the director of the government efficiency division of the state budget office, said that it was difficult to say whether the state would have actually lost those jobs without the money.

homelessness rises, redefining living conditions for schoolchildren

Chicago Tribune | Maria Maior's son is a football-playing, skateboard-riding, Xbox-loving kid whose home reveals all the trappings of domesticity: a cushy sofa, big-screen TV, a framed poster of Brian Urlacher -- one of the 12-year-old's favorite football players. On most evenings, two big dogs curl up on the carpeting.

The scene could be lifted from any suburban subdivision -- except that it's located not in a den, but in a storage unit.

The boy moved into the 10-foot-by-25-foot bunker about two months ago with his mom and her fiance, after a long run of bad luck and the loss of both of their jobs. His mother didn't not want his name used for this article. "As long as I have my parents, I'm fine with this," Maior's son said of the accommodations. "It's really not that bad."

School district officials said the boy is one of a record number of area students living in motels, campgrounds, shelters, cars and, yes, storage facilities.

According to recently released data, McHenry County's homeless enrollment increased by 125 percent from the 2007-08 school year to the 2008-09 school year -- the biggest hike in the six-county metropolitan area. Schools in Kane (85 percent), Will (61 percent), DuPage (53 percent), Lake (44 percent) and suburban Cook (24 percent) counties also posted their largest increases, reflecting the surge in foreclosures and unemployment. Early reports indicate that the trend has continued this fall, with numbers spiraling even higher