new intelligence

Part 1A

Part 1B

Part 1C

Part 1D

Part 1E

JanCox | New Intelligence does not come about through more reading or more studying, but through more thinking -- all the time, and flexibly at that. If you were to try to explain this to someone at the ordinary level, in ordinary terms, it would sound ridiculous. If anyone listening at the ordinary level were to hear that there is something like New Intelligence, they would think that it came about through some sort of studying. Ordinary consciousness would ask how to get New Intelligence, and after hearing the explanation, would start to study it. In fact, a busy person might ask for something to read so that they could reference it later and then study it.

New Intelligence will not be developed by reading or studying of any sort. NO WAY! The approach is simply to THINK MORE. To this statement, good old ordinary intelligence would reply, "But I think all the time as it is!" We're not going to question ordinary 3-Dimensional judgements about measuring the quantity of time spent thinking, but it is important to remember that there is as much quantity as there is space. There are no empty places, no empty spaces. Everywhere that ordinary 3-D consciousness can look there is stuff filling up space.

Although it appears otherwise to 3-D consciousness, there is no sense saying, quantitatively speaking, that there are no empty spaces in one's thinking schedule. It simply is not the case that there are no empty thinking spaces. Even if that were true, you've got to think more -- you've got to think all the time. Every moment you have to think more. All right, you believe you're thinking all the time -- but you've got to think some more. Once you try to think more, you will find out that you can take whatever space seems to be filled up, and put in more.

It is part of the illusionary reality of the 3-D world that more can be put into whatever space appears to be already filled up. (Ordinary consciousness does not want to put in more, though, because that would mean "playing in the key of CHANGE," which everyone fears and dreads.) The forced new additional thinking has got to be done all the time, and it must be flexible. Then you are on the way to developing a new kind of intelligence.

Whatever is going on, you should be thinking, involved in a continual asking of yourself, "Why -- to what end from a 4-D level -- is such-and-such going on?" You must think with a sweeping, omnidirectional sort of consciousness. For instance, first thing in the morning as you are getting ready, think about everything you have to do that day (not in a worrisome manner), while simultaneously brushing your teeth, combing your hair, keeping your eye on the clock, listening to the radio to check their time against the clock time, listening to whether the coffee is perking yet, thinking of all that you might do today if you have time, and so on. Don't think of things linearly, in sequence, but in a nonordinary way; think of them all together, at the same time, continually, all the time.

optogenetic neurophysiology

SciAm | as our understanding of the brain grows, our desire to intervene, to help ameliorate the many pathologies to which the mind is prey, grows commensurately. Yet today’s tools (drugs and deep-brain stimulations) are comparatively crude, with undesirable side effects.

To the rescue rides an amazing technology, a fusion of molecular biology with optical stimulation, dubbed optogenetics. It is based on some fundamental discoveries made by three German biophysicists—Peter Hegemann, Ernst Bamberg and Georg Nagel working on photoreceptors in ancient bacteria. These photoreceptors directly (rather than indirectly, like the ones in your eyes) convert incoming light in the blue part of the spectrum into an excitatory, positive electrical signal. The trio also isolated the gene for this protein, called channelrhodopsin-2 (ChR2). Bamberg and Nagel subsequently engaged in a fruitful collaboration with Karl Deisseroth, a professor of psychiatry and bioengineering at Stanford University, and Edward S. Boyden, now at the Massachusetts Institute of Technology.

The group took the ChR2 gene, inserted it into a small virus, and infected neurons with this virus. Many of the neurons took up the foreign instructions, synthesized ChR2 protein and inserted the photoreceptors in their membrane. In the dark, the receptors quietly sit there, with no discernible effect on their host cells. But illumination of the network with a brief flash (10 milliseconds) of blue light causes each of these bacterial photoreceptors to jolt their host cell a bit. Collectively, they reliably and repeatedly produce a spike in the membrane voltage. Spikes are the universal all-or-none pulses used by all but the tiniest nervous systems to communicate information among neurons. Each time the light is turned on, the cells spike reliably, exactly once. Thus, an entire population of neurons can be manipulated by precisely timed stabs of light.

The biophysicists added another photoreceptor to their tool kit. It derives from a different type of bacterium, one living in dry salt lakes in the Sahara Desert. Shining yellow light on it yields an inhibitory, negative signal. Through the same viral strategy, both photoreceptor types were then introduced into neurons. Once the neuron stably incorporates both types into its membrane, it can be excited by blue light and subdued by yellow. Each blue flash evokes a spike, like a note sounding when a piano key is pushed down. But a simultaneous flash of yellow light can block that spike. Consider the “musical score sheet” recorded from one such neuron as it is played with light. This ability to precisely control electrical activity in one or more neurons is unprecedented.

g.i. gurdjieff

Wikipedia | Gurdjieff argued that many of the existing forms of religious and spiritual tradition on Earth had lost connection with their original meaning and vitality and so could no longer serve humanity in the way that had been intended at their inception. As a result humanity were failing to realize the truths of ancient teachings and were instead becoming more and more like automatons, susceptible to control from outside and increasingly capable of otherwise unthinkable acts of mass psychosis such as the 1914-18 war. At best, the various surviving sects and schools could only provide a one-sided development which did not result in a fully integrated human being. According to Gurdjieff, only one dimension of the person - namely, the emotions, the physical body or the mind - tends to be developed in such schools and sects and generally at the expense of the other faculties or centers as Gurdjieff called them. As a result these paths fail to produce a proper balanced human being. Furthermore, anyone wishing to undertake any of the traditional paths to spiritual knowledge (which Gurdjieff reduced to three - namely the path of the fakir, the path of the monk, and the path of the yogi) were required to renounce life in the world. Gurdjieff thus developed a Fourth Way which would be amenable to the requirements of modern people living modern lives in Europe and America. Instead of developing body, mind, or emotions separately, Gurdjieff's discipline worked on all three to promote comprehensive and balanced inner development.

In parallel with other spiritual traditions, Gurdjieff taught that one must expend considerable effort to effect the transformation that leads to awakening. The effort that one puts into practice Gurdjieff referred to as "The Work" or "Work on oneself". According to Gurdjieff, "...Working on oneself is not so difficult as wishing to work, taking the decision." Though Gurdjieff never put major significance on the term "Fourth Way" and never used the term in his writings, his pupil P.D. Ouspensky from 1924 to 1947 made the term and its use central to his own teaching of Gurdjieff's ideas. After Ouspensky's death, his students published a book titled The Fourth Way based on his lectures.

Gurdjieff's teaching addressed the question of humanity's place in the universe and the importance of developing latent potentialities — regarded as our natural endowment as human beings but rarely brought to fruition. He taught that higher levels of consciousness, higher bodies, inner growth and development are real possibilities that nonetheless require conscious work to achieve.

In his teaching Gurdjieff gave a distinct meaning to various ancient texts such as the Bible and many religious prayers. He claimed that those texts possess a very different meaning than what is commonly attributed to them. "Sleep not"; "Awake, for you know not the hour"; and "The Kingdom of Heaven is Within" are examples of biblical statements which point to a psychological teaching whose essence has been forgotten.

Gurdjieff taught people how to increase and focus their attention and energy in various ways and to minimize daydreaming and absentmindedness. According to his teaching, this inner development in oneself is the beginning of a possible further process of change, the aim of which is to transform people into what Gurdjieff believed they ought to be.

Distrusting "morality", which he describes as varying from culture to culture, often contradictory and superficial, Gurdjieff greatly stressed the importance of conscience. This he regarded as the same in all people, buried in their subconsciousness, thus both sheltered from damage by how people live and inaccessible without "work on oneself".

To provide conditions in which inner attention could be exercised more intensively, Gurdjieff also taught his pupils "sacred dances" or "movements", later known as the Gurdjieff movements, which they performed together as a group. He also left a body of music, inspired by what he heard in visits to remote monasteries and other places, written for piano in collaboration with one of his pupils, Thomas de Hartmann. Gurdjieff also used various exercises, such as the "Stop" exercise, to prompt self-observation in his students. Other shocks to help awaken his pupils from constant day-dreaming were always possible at any moment.

sista dr. teresa forcades drops knowledge on the flu

genomics richard stallman?

The Scientist | In the future, Hubbard says that gene-prediction programs need to get good enough that they can find genes without the aid of experimental data or comparative genome analyses to guide them. “Because that’s cheating,” he says. “For example, an RNA polymerase does not go and look at the mouse genome when it’s working out whether to transcribe a particular stretch of human sequence. But that’s what many of our algorithms do now.” Instead, he says that annotation programs should take an RNA polymerase–eye-view of the sequence, modeling the biology closely enough to accurately locate and assess the activity of genes. As we move into an era of personal genomics, such an approach will be necessary for predicting the effect that a certain SNP variant might have on gene function. He and his team have had some early success, producing a transcription start-site predictor that nails about half the genes in a genome sequence with very few false positives.

Hubbard also spends quite a bit of time working on issues of open access and the economics of innovation. “Governments are spending all this money for research and then not maximizing its value because they’re not investing enough in making sure people can access and reuse that data,” says Hubbard, who has discussed these issues at meetings of the Organisation for Economic Cooperation and Development (OECD) and the World Health Organization. Much of this work he does in his spare time. “Other people go fishing,” laughs Birney. “Tim likes to reform international patent law and go to UN conferences to discuss how open-access agreements should be arranged to maximize the way science gets translated into meaningful outcomes.”

Those outcomes, of course, include potential improvements in the diagnosis and treatment of disease, which makes the issue more urgent and more fraught. “If you look at the health implications of all the work being done in genomics, the opportunities are tremendous and the obstacles are staggering—and a lot of those are political,” says Haussler. “I just have the ultimate respect for Tim, as he’s willing to move through those political hurdles and try to get things to happen.”

“In a way, Tim’s contribution to the scientific endeavor is a very interesting one and rather different from most scientists,” says EBI director Janet Thornton. “Although he’s had a hand in producing many of the big genome publications, his unique input lies in his broad perspective, his sense of fairness, and his openness to new ideas. His diplomatic efforts have really been fundamental in making these large-scale, collaborative genomics projects work—and in making the data available so that the science can be put to good use for biology and medicine around the world.”

“A lot of things can be done by one person with a computer,” adds Flicek. “If the Internet age taught us anything, it’s taught us that.”

art of the samurai

MMOA | This will be the first comprehensive exhibition devoted to the arts of the samurai. Arms and armor will be the principal focus, bringing together the finest examples of armor, swords and sword mountings, archery equipment and firearms, equestrian equipment, banners, surcoats, and related accessories of rank such as fans and batons. Drawn entirely from public and private collections in Japan, the majority of objects date from the rise of the samurai in the late Heian period, ca. 1156, through the early modern Edo period, ending in 1868, when samurai culture was abolished. The martial skills and daily life of the samurai, their governing lords, the daimyo, and the ruling shoguns will also be evoked through the presence of painted scrolls and screens depicting battles and martial sports, castles, and portraits of individual warriors. The exhibition will conclude with a related exhibition documenting the recent restoration in Japan of a selection of arms and armor from the Metropolitan Museum’s permanent collection. This will be the first exhibition ever devoted to the subject of Japanese arms and armor conservation.
Accompanied by a catalogue.

The exhibition is made possible by the Yomiuri Shimbun.

blue-collar scholar spits game

Democracy Now | William Black, Former bank regulator at the Federal Savings and Loan Insurance Corporation. In the 1980s he helped expose the savings and loan scandal. He now teaches at the University of Missouri–Kansas City and is the author of the book The Best Way to Rob a Bank Is to Own One: How Corporate Executives and Politicians Looted the S&L Industry. Interview money shot;

WILLIAM BLACK: Well, I mean, Summers, for example—you talked about Geithner’s aides and how much money they had made, and, of course, it’s absurdly large, and they’re making it typically for not doing much of anything. But they’re taking their cue from Summers, who got $5 million, roughly, for working one day a week in areas he had no expertise. So, you know, once you leave the federal service, then these interests that you were very helpful to find a way to make you spectacularly rich, and they know that that’s what’s coming in their future. That’s part of the problem.

But the bigger part of the problem, in many ways, is that they have such an ideology about the market and its ability to deal with all problems that has no basis in reality, has been exposed in this crisis as completely fictional, and yet they can’t give it up. I mean, think of yourself as one of these professors who’s been trained in the Milton Friedmanish views, and you’re in your fifties, and you’ve been saying—you know, everything you’ve said in your career is wrong. Everything you’ve learned in your career is wrong. All of your areas of expertise are wrong. Are you going to admit that? “Hi, I’ve been misleading you, and I’m sorry I caused this disaster. And by the way, I have no meaningful skills or experience.”

As Foreclosures Hit All-Time High, Wall Street on Pace to Hand Out Record $140B in Employee Bonuses - The Dow Jones Industrial Average has topped 10,000 for the first time in a year, as JPMorgan Chase reported massive profits in the third quarter. Meanwhile, the Wall Street Journal is reporting that major US banks and securities firms are on pace to pay their employees about $140 billion this year—a record high. But on Main Street, foreclosures are also at record levels, and the official unemployment rate is expected to top ten percent.

simply brilliant....,

The Scientist | A project at Harvard Medical School aims to bring music to medicine in a way that goes beyond setting the mood in the waiting room. Gene transcription and translation are anything but simple. But by combining modern statistics with the sounds of a sweet melody, bioinformatician Gil Alterovitz may make interpreting these complex phenomena and diagnosing the diseases that result from abnormalities in gene expression much more manageable tasks.

"I think it's brilliant that Gil is using a completely different channel for communicating complex genomic information," Latin and ballroom DJ Taro Muso writes in an email to The Scientist. "I've always wondered why doctors don't seem to use their ears beyond listening for natural bodily sounds."

"It's deceptively simple," says bioinformatician Yves Lussier of the University of Chicago. "It was conceptually challenging to come up with it, but once we know of it, it's obvious we should have tried that in addition to visualization techniques we have been using."

By boiling down gene expression data to just a few components -- variables that condense one or more parameters of data -- and assigning each of those components a different note and musical instrument, Alterovitz and his colleagues are literally making genetics musical.

The team carefully chooses the notes such that normal gene expression patterns sound pleasantly in tune, while abnormal data yield discordant sounds. "When you hear inharmonious music it kind of catches your attention," Alterovitz says, "and that would be a sign of a pathological problem."

"Even amateur musicians can tell the difference between various chords," Muso agrees, "so there is a definite potential for motivated biologists to use harmony as a screening method."

Alterovitz got the idea ten years ago while doing his PhD at the Massachusetts Institute of Technology. When he donned his scrubs and joined surgeons in the operating room as part of his graduate research project, he was distracted by the numerous monitors measuring nearly two dozen biological signals. Sometimes an alarm would go off, he recalls, but most of the time it wasn't really relevant, and they were simply turned off and ignored.

"Wouldn't it be useful if we somehow integrated [all] those variables so that we could present something that was not just a binary alarm but holistic information about the whole system?"

building better bacteria

The Scientist | Researchers from the J. Craig Venter Institute have developed a technique for generating modified strains of bacteria with novel, genetically engineered properties, they report online today (August 20) in Science. The advance could help scientists tweak microorganisms to more efficiently produce biofuels, the researchers say.

"I think it's an important and interesting advance," said James Collins, a bioengineer at Boston University who was not involved in the study. "I suspect this will turn out to be quite important for bioengineering and bioenergy systems."

Last year, Venter, an author on the paper (and a member of The Scientist's editorial board), reported that he and his collaborators had created a synthetic bacterial genome and cloned it into a yeast cell. However, they were unable to transfer the genome into a cell that would use the genetic code to produce a functioning version of the organism. In the current paper, the researchers present a technique for doing just that.

The Venter team first cloned the genome of the bacterium Mycoplasma mycoides into a yeast cell. They then altered the genome, using the myriad tools available for yeast gene manipulation. In the procedure's trickiest step, they transplanted the yeast-bound bacterial genome into a closely related bacterium, Mycoplasma capricolum, coaxing it to "take this bacterial genome and boot it up" and generate their mutant strain, said Sanjay Vashee, a synthetic biologist at the institute and the corresponding author on the paper.

The hurdle Vashee and his team had to overcome to achieve this feat involved bypassing the bacterial equivalent of an immune system -- essentially a collection of restriction enzymes. These enzymes, thought to have evolved to chew up the genomes of viruses infecting bacterial cells, were preventing the successful transplantation of the modified M. mycoides genome into wild-type M. capricolum. So the group developed two fixes, which together solved the problem: First, they inactivated M. capricolum's restriction enzymes. Then, they chemically modified their mutant M. mycoides genome where these enzymes typically cleave the genomes of intruders.

Decades of research on yeast genetics have yielded the know-how to do extensive genomic manipulations in yeast, but that capability doesn't exist for other microorganisms. "There are so many organisms in nature that we cannot manipulate," said Vashee. "If we can extend this -- and put those genomes into yeast, to manipulate them there -- we've got a new technology that can bring genomics to a wide host of organisms." (Vashee noted that the current study was conducted in a natural Mycoplasma genome -- not the synthetic genome the group assembled last year.)

what's really wrong with american healthcare?

The Atlantic | After the needless death of his father, the author, a business executive, began a personal exploration of a health-care industry that for years has delivered poor service and irregular quality at astonishingly high cost. It is a system, he argues, that is not worth preserving in anything like its current form. And the health-care reform now being contemplated will not fix it. Here’s a radical solution to an agonizing problem.

How does a nation that might close down a business for a single illness from a suspicious hamburger tolerate the carnage inflicted by our hospitals? And not just those 100,000 deaths. In April, a Wall Street Journal story suggested that blood clots following surgery or illness, the leading cause of preventable hospital deaths in the U.S., may kill nearly 200,000 patients per year. How did Americans learn to accept hundreds of thousands of deaths from minor medical mistakes as an inevitability?

My survivor’s grief has taken the form of an obsession with our health-care system. For more than a year, I’ve been reading as much as I can get my hands on, talking to doctors and patients, and asking a lot of questions.

Keeping Dad company in the hospital for five weeks had left me befuddled. How can a facility featuring state-of-the-art diagnostic equipment use less-sophisticated information technology than my local sushi bar? How can the ICU stress the importance of sterility when its trash is picked up once daily, and only after flowing onto the floor of a patient’s room? Considering the importance of a patient’s frame of mind to recovery, why are the rooms so cheerless and uncomfortable? In whose interest is the bizarre scheduling of hospital shifts, so that a five-week stay brings an endless string of new personnel assigned to a patient’s care? Why, in other words, has this technologically advanced hospital missed out on the revolution in quality control and customer service that has swept all other consumer-facing industries in the past two generations?

I’m a businessman, and in no sense a health-care expert. But the persistence of bad industry practices—from long lines at the doctor’s office to ever-rising prices to astonishing numbers of preventable deaths—seems beyond all normal logic, and must have an underlying cause. There needs to be a business reason why an industry, year in and year out, would be able to get away with poor customer service, unaffordable prices, and uneven results—a reason my father and so many others are unnecessarily killed.

Before exploring alternative policies, let’s reexamine our basic assumptions about health care—what it actually is, how it’s financed, its accountability to patients, and finally its relationship to the eternal laws of supply and demand. Everyone I know has at least one personal story about how screwed up our health-care system is; before spending (another) $1trillion or so on reform, we need a much clearer understanding of the causes of the problems we all experience.

new non-drug fix for HIV?

The Scientist | Researchers are slowly establishing a connection between an extremely rare genetic disease and HIV -- and homing in on a safe, non-prescription compound that could treat both.

Recently, James Hildreth at the Meharry Medical College School of Medicine in Nashville, Tenn., and his colleagues found that cells affected by Niemann-Pick Type C (NPC), which disrupts cholesterol trafficking, were unable to release HIV, suggesting these cells would not spread the virus.

These findings, published May 27 in the Journal of Virology, are rooted in a hypothesis Hildreth has explored for a long time: that "cholesterol is somehow essential" to HIV, he said. For instance, HIV-1 relies on specialized structures known as lipid rafts, which are rich in cholesterol, to infect new cells.

That line of thinking has led him to investigate whether a compound widely employed by the food and chemical industries (and used as a drug solubilizer) which depletes cells of cholesterol could serve as a preventative agent -- or even a treatment -- for HIV. And his growing body of evidence is suggesting the compound, known as cyclodextrin, might do just that.

"There are very few [compounds] that rival the safety profile" of cyclodextrin, said Hildreth. If further research confirms it has an effect on a disease that affects millions of people worldwide, that would be a major advance, he noted. "It's been exciting for me from the beginning."

coon man

Detroit News | When selecting the best raccoon carcass for the special holiday roast, both the connoisseur and the curious should remember this simple guideline: Look for the paw.

"The paw is old school," says Glemie Dean Beasley, a Detroit raccoon hunter and meat salesman. "It lets the customers know it's not a cat or dog."

Beasley, a 69-year-old retired truck driver who modestly refers to himself as the Coon Man, supplements his Social Security check with the sale of raccoon carcasses that go for as much $12 and can serve up to four. The pelts, too, are good for coats and hats and fetch up to $10 a hide.

While economic times are tough across Michigan as its people slog through a difficult and protracted deindustrialization, Beasley remains upbeat.

Where one man sees a vacant lot, Beasley sees a buffet.

"Starvation is cheap," he says as he prepares an afternoon lunch of barbecue coon and red pop at his west side home.

His little Cape Cod is an urban Appalachia of coon dogs and funny smells. The interior paint has the faded sepia tones of an old man's teeth; the wallpaper is as flaky and dry as an old woman's hand.

Beasley peers out his living room window. A sushi cooking show plays on the television. The neighborhood outside is a wreck of ruined houses and weedy lots.

"Today people got no skill and things is getting worse," he laments. "What people gonna do? They gonna eat each other up is what they gonna do."

A licensed hunter and furrier, Beasley says he hunts coons and rabbit and squirrel for a clientele who hail mainly from the South, where the wild critters are considered something of a delicacy.

terrorism's tragic toll...,

fist tap to Submariner MD.

h1n1 systematization

Northwestern ROCS | In our simulations for the spread in the United States we take Mexico City to be the starting point of the infection. The initial conditions of the model are chosen to match the available information on confirmed cases in the United States and Mexico, and we permit for a bracket of unconfirmed cases. We take into account the travel of individuals between counties in the United States and the incoming flux of airline passengers from Mexico City. We consider a worst-case scenario based on assumptions made from the information we have gathered thus far. The key factors in our modeling approach are very accurate human mobility datasets on scales from a few to a few thousand kilometers. We obtained the underlying multi-scale human mobility network indirectly by our recent investigation on the geographic circulation of dollar bills in the United States, which is an excellent proxy for human mobility and includes small scale daily commuting traffic, intermediate traffic, and long distance travel by air. Our simulations consist of multiple layers, each layer possessing and increasing degree of accuracy and complexity. Our final projections are done with a fully stochastic model that incorporates the inherent randomness in disease dynamics that is particularly important at the onset of an epidemic when the number of infected individuals is small compared to the whole population.

emergency medicine backchannel scoop...,

After I returned from a public health meeting yesterday with community leaders and school officials in Comal County and Hays County, Heather suggested I send an update to my patients in the area, because what we are hearing privately from the CDC and Health Department is different from what you are hearing in the media. Some of you know some of this, but I will just list what facts I know.

- The virus is infectious for about 2 days prior to symptom onset

- Virus spreads more than 7 days after symptom onset (possibly as long as 9 days) (this is more unusual than ordinary flu)

- Since it is such a novel (new) virus, th ere is no "herd immunity," so the "attack rate" is very high. This is the percentage of people who come down with a virus if exposed. Almost everyone who is exposed to this virus will become infected, though not all will be symptomatic. That is much higher than seasonal flu, which averages 10-15%. The "clinical attack rate" estimation from CDC and WHO may be around 40-50%. This is the number of people who show symptoms. This is a huge number. It is hard to convey the seriousness of this to those outside of the medical fields.

- The virulence (deadliness) of this virus is as bad here as in Mexico, and there are folks on ventilators here in the US, right now. This has not been in the media, but a 23 month old in Houston is fighting for his life, and a pregnant woman just south of San Antonio is fighting for her life. In Mexico, these folks might have died already, but here in the US, folks are getting Tamiflu or Relenza quickly, and we have ready access to ventilators. What this means is that within a couple of weeks, regional hospitals will likely become overwhelmed.

- Some of the kids with positive cases in Comal County have had more than 70 contacts before diagnosis as a minimum figure.

- There are 10-25 times more actual cases (not "possible" cases -- actual), than what is being reported in the media. The way they fudge on reporting this is that it takes 3 days to get the confirmatory nod from the CDC on a given viral culture, but based on epidemiological grounds, we know that there are more than 10 cases for each "confirmed" case right now.

- During the night, we crossed the threshold for the definition of a WHO, Phase 6 global pandemic. This has not happened in any of our lifetimes so far. We are in uncharted territory.

- They are advising President Obama to declare an emergency sometime in the next 72-96 hours. This may not happen, but if it doesn't, I will be surprised. When this happens, all public gathering will be cancelled for 10 days minimum.

- I suggest all of us avoid public gatherings. Outdoor activities are not as likely to lead to infection. It is contained areas and close contact that are the biggest risk.

- Tamiflu is running out. There is a national stockpile, but it will have to be carefully managed for law enforcement and first responders as it is not enough to treat the likely number of infections when this is full-blown. I don't think there is a big supply of Relenza, but I do not know those numbers. If I had to choose, I would take Relenza, as I think it gets more drug to the affected tissue than Tamiflu.

- You should avoid going to the ER if you think you have been exposed or are symptomatic. ER's south of here are becoming overwhelmed today-- and I mean that -- already. It is coming in waves, but the waves are getting bigger.

- It appears that this flu produces a distinctive "hoarseness" in many victims. The symptoms, in general, match other flu's; namely, sore throat, body aches, headache, cough, and fever. What is not too common in regular flu cycles is vomiting and diarrhea which seems to be associated with this, further dehydrating victims. Some have all these symptoms, while others may have only one or two.

- N-Acetyl-Cysteine -- a nutritional supplement available at the health food store or Wimberley Pharmacy, has been shown to prevent or lessen the severity of influenza. I suggest 1200mg, twice a day for adults, and 600mg twice a day in kids over 12. It would be hard to get kids under 12 to take it, but you could try opening the capsules and putting it on yogurt. For 40 pounds and up, 300-600 mg twice a day, for less than 40 pounds, half that.

- Oscillococinum, a homeopathic remedy, has been vindicated as quite effective in a large clinical trial in Europe, with an H1N1 variant. You can buy this at Hill Country Natural Foods, or the Wimberley Pharmacy.

I will try to keep everyone posted if I have any new information. Meanwhile, don't be afraid, stay informed and try to avoid infection. The fewer people infected the easier it will be for our public officials to manage it.

If any of my patients become ill, or suspect infection, call the office, do not come without calling and DO NOT go to the ER. If one member in a family is identified all would be given the Tamiflu or Relenza (that is normal course of action) if there is enough distributed to fill prescriptions. Public health stated that one family member identified or suspected to have contracted the flu it will require the whole family to be ‘quarantined’ in their own home until enough time has passed for the remaining household to have contracted it or be considered infection free ( 7 to 10 days per person). As another suggestion, if any member of the family is on routine medication- fill those prescriptions now. Have plenty fluids, Motrin, soups, etc available and make contingency plans in case your family is affected.

folk medicines and herbs to use and avoid with flu

Health Gazette | Below is a list of foods that are said to contain substances that are natural antivirals, immune boosters or they decrease cytokines TNF-a and IL-6.

Alternative medications that are most likely to help us during a severe pandemic:

Garlic (allicin) - Very effective antiviral. Best if fresh (raw) and crushed. Must be consumed within 1 hour of crushing. Dosage is initially 2 to 3 cloves per day but later reduce until no body odour occurs. No toxic effects noted. (Pubmed PMID 9049657)

Vitamin C - Boosts the immune system and is an antiviral by blocking the enzyme neuraminadase. Viruses need neuraminadase to reproduce. There are anecdotal stories of people taking large amounts of Vitamin C (children ½) surviving the Spanish Flu. Research shows that it may reduce the production of cytokines TNF-a and IL-6. A study on 470 people involved giving the test group 1000 mg hourly for 6 hours and then 1000 mg 3 times daily after reporting flu symptoms. Symptoms decreased by 85%. (Pubmed PMID 10543583, 634178, 16169205, 12876306)

Green Tea (possible Tamiflu/Relenza alternative)- Very effective antiviral. Also decreases the production of the cytokine (catechins) TNF-a. Inhibits neuraminidase. May have antiviral activity that is equal to other antivirals such as Tamiflu. (Pubmed PMID 16137775)

St Johns Wort (Hypericum) - Very effective antiviral. Also decreases the production of the cytokine IL-6. Hypericum is an extract from St John’s Wort. There have been some very successful field trials in commercial flocks infected with H5N1 in Vietnam. (Pubmed PMID 7857513, 11518071, 11362353, 7857513, 11518071)

Vitamin E - Immune booster. Also decreases the production of the cytokine TNF-a. (Pubmed PMID 155882360, 10929076) Experiments involved using mice. Very suitable for immune compromised people, especially the elderly. Effects enhanced when taken with Vitamin C.

Apple Juice - Antiviral. Fresh apple juice including the pulp and skin has greater antiviral activity than heated commercial apple juice. More research is needed. Effectiveness on H5N1 is unknown. (Pubmed PMID 32832, 12452634)

Resveratrol - Antiviral. In addition to inhibiting neuraminidase, Resveratrol also sends a message to cells to stop manufacturing viruses. This is a proven antiviral found naturally in red wine, peanuts, mulberries, Japanese Knotwood root (richest source), raisins and red grapes. Resveratrol supplements are relatively inexpensive, are more stable than wine and is available in liquid form for absorption in the mouth. No toxic effects noted. (Pubmed PMID 1583880, 12817628, 15985724)

Scuttellaria (Skullcap) - Antiviral. A herb used as a tea. It has no side effects and is also a mild tranquilliser. Research suggests neuraminidase, which is a substance needed by the H5N1 virus to reproduce, may be inhibited.

Cranberry Juice - Early research shows that it may be an antiviral, making viruses less able to invade or multiply. Effectiveness on H5N1 is unknown. (Pubmed PMID15781126)

Cat’s Claw (Uncaria tomentosa) - Decreases the production of the cytokine TNF-a. Also boosts immune system. The number of white blood cells was significantly increased during treatment. No toxicity was noted. (http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed) Active constituents can be found in the leaves, bark, vine, and roots. Water extraction from bark used. Children and pregnant women are to avoid. Has a potentially damaging effect on the DNA of proliferating cells. (cancers, foetuses, growing children)

Curcumin (Tumeric Spice) - Decreases the production of the cytokine TNF-a. This is the yellow compound in turmeric spice. Research shows that this may be very good for preventing a cytokine storm although this is not proven. Must be taken with food or gastritis or peptic ulcers may occur. Pregnant women and feeding mothers should avoid this. The medicinal properties of curcurnin cannot be utilised when used alone due to rapid metabolism in the liver and intestinal wall. When combined with Piperine found in black pepper the absorption is increased with no adverse effects. Obtainable from health stores in tablets, liquid, capsules already combined with piperine. Dosage is 500mg to 4000mg daily.

Astragalus root (Astragali Radix) - Boosts immune system. (Pubmed PMID15588652)

Tea tree Steam Inhalation - Reduces the cytokine TNF-a. Add 2 drops of tea tree oil in a bowl of steaming water. Cover head with a towel and inhale for 5 to 10 minutes. Relieves congestion and fights infection. Its effectiveness is unknown. (Pubmed PMID 11131302)

The following substances may be best to avoid during a H5N1 pandemic

Elderberry juice (Sambucal) - AVOID - Increases production of cytokines TNF-a and IL-6. This substance is very effective against the common flu but may not be desirable for the H5N1 virus. Increases in these cytokines may trigger a lethal cytokine storm. (Isr Med Journal2002 Nov;4:944-6)

Micro Algae (Chlorella and Spirulina) - AVOID - Increases production of cytokine TNF-a. (Pubmed PMID 11731916)

Honey - AVOID - Increases production of cytokines TNF-a and IL-6. (Pubmed PMID12824009)

Chocolate - AVOID - Increases production of cytokines TNF-a and IL-6. (Pubmed PMID 12885154, PMID 10917928)

Echinacea - AVOID - Increases production of cytokines TNF-a and IL-6. Although it is often used for normal flu, research shows that it may increase the chance of cytokine storms for H5N1. (Pubmed PMID 15556647, 9568541)

Kimchi - AVOID - Increases production of cytokines TNF-a and IL-6. (Pubmed PMID15630182)

Dairy products & Bananas - AVOID - These foods increase mucous production.

so busted....,

NYTimes | FOR seven years I have remained silent about the false claims magnifying the effectiveness of the so-called enhanced interrogation techniques like waterboarding. I have spoken only in closed government hearings, as these matters were classified. But the release last week of four Justice Department memos on interrogations allows me to shed light on the story, and on some of the lessons to be learned.

One of the most striking parts of the memos is the false premises on which they are based. The first, dated August 2002, grants authorization to use harsh interrogation techniques on a high-ranking terrorist, Abu Zubaydah, on the grounds that previous methods hadn’t been working. The next three memos cite the successes of those methods as a justification for their continued use.

It is inaccurate, however, to say that Abu Zubaydah had been uncooperative. Along with another F.B.I. agent, and with several C.I.A. officers present, I questioned him from March to June 2002, before the harsh techniques were introduced later in August. Under traditional interrogation methods, he provided us with important actionable intelligence.

We discovered, for example, that Khalid Shaikh Mohammed was the mastermind of the 9/11 attacks. Abu Zubaydah also told us about Jose Padilla, the so-called dirty bomber. This experience fit what I had found throughout my counterterrorism career: traditional interrogation techniques are successful in identifying operatives, uncovering plots and saving lives.

There was no actionable intelligence gained from using enhanced interrogation techniques on Abu Zubaydah that wasn’t, or couldn’t have been, gained from regular tactics. In addition, I saw that using these alternative methods on other terrorists backfired on more than a few occasions — all of which are still classified. The short sightedness behind the use of these techniques ignored the unreliability of the methods, the nature of the threat, the mentality and modus operandi of the terrorists, and due process.

h.r. 875 stupidity...,

Ran Prieur | March 9. Everybody chill out about H.R. 875. That link goes to a full paranoid analysis on Cryptogon. In theory, this law could have federal agents stomping through your vegetable garden and fining you a million dollars for failing to get a permit. In practice, this is a move by occult trickster entities to grow and harvest emotions of fear and victimization from the fertile soil of the foilhead crowd.

I swear, anti-government people worship the government. Nobody else has such unwavering belief in the government's omniscience and omnipotence. Anything the government writes on paper is assumed to be magically done. This analysis on Campaign for Liberty says the law "will literally put all independent farmers and food producers out of business due to the huge amounts of money it will take to conform to factory farming methods." You know, you don't have to do everything you're told. Why not say instead that this will put the government out of business due to the huge amounts of money it will take to enforce the law against millions of small food producers?

We're in the position of strength here. Look at all the ways the file sharers have dodged the copyright cartel, and they're sharing fragile high-tech artifacts that require sophisticated computer equipment and electricity. We're sharing life, seeds that can remain viable for hundreds of years, plants that need only dirt and water and sunlight, animals that can live on table scraps in the garage, species that have duplicated themselves, in many cases without human help, for thousands or millions of years. Look at what happened when they tried to eradicate cannabis, and imagine them trying to fight the same war on a thousand fronts, never mind the tens of thousands of species they don't even know are edible. Seriously, I hope the agriculture giants really do try to stop all independent food production, because we will stuff them in the compost bin of history.

introducing wolfram alpha

Twine | In a nutshell, Wolfram and his team have built what he calls a "computational knowledge engine" for the Web. OK, so what does that really mean? Basically it means that you can ask it factual questions and it computes answers for you.

It doesn't simply return documents that (might) contain the answers, like Google does, and it isn't just a giant database of knowledge, like the Wikipedia. It doesn't simply parse natural language and then use that to retrieve documents, like Powerset, for example.

Instead, Wolfram Alpha actually computes the answers to a wide range of questions -- like questions that have factual answers such as "What is the location of Timbuktu?" or "How many protons are in a hydrogen atom?," "What was the average rainfall in Boston last year?," "What is the 307th digit of Pi?," "where is the ISS?" or "When was GOOG worth more than $300?"

Think about that for a minute. It computes the answers. Wolfram Alpha doesn't simply contain huge amounts of manually entered pairs of questions and answers, nor does it search for answers in a database of facts. Instead, it understands and then computes answers to certain kinds of questions.

(Update: in fact, Wolfram Alpha doesn't merely answer questions, it also helps users to explore knowledge, data and relationships between things. It can even open up new questions -- the "answers" it provides include computed data or facts, plus relevant diagrams, graphs, and links to other related questions and sources. It also can be used to ask questions that are new explorations between relationships, data sets or systems of knowledge. It does not just provides textual answers to questions -- it helps you explore ideas and create new knowledge as well)